Gene description for RGD1561212
Gene name similar to RIKEN cDNA 4732496O08
Gene symbol RGD1561212
Other names/aliases -
Species Rattus norvegicus
 Database cross references - RGD1561212
ExoCarta ExoCarta_502976
Entrez Gene 502976
 RGD1561212 identified in exosomes derived from the following tissue/cell type
Pancreatic cancer cells 20124479    
Pancreatic cancer cells 20124479    
 Gene ontology annotations for RGD1561212
Molecular Function
    retinoic acid receptor binding GO:0042974 IEA
Biological Process
    negative regulation of apoptotic process GO:0043066 IEA
    negative regulation of retinoic acid receptor signaling pathway GO:0048387 IEA
    negative regulation of transcription, DNA-templated GO:0045892 IEA
    negative regulation of cell differentiation GO:0045596 IEA
    positive regulation of cell proliferation GO:0008284 IEA
 Experiment description of studies that identified RGD1561212 in exosomes
1
Experiment ID 92
ISEV standards
EM
EV Biophysical techniques
HSP70|GAPDH
EV Cytosolic markers
CD9|CD151
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 20124479    
Organism Rattus norvegicus
Experiment description Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Authors Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M, Lochnit G, Preissner KT, Zoller M.
Journal name CR
Publication year 2010
Sample Pancreatic cancer cells
Sample name AS
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14-1.17 g/mL
Molecules identified in the study Protein
mRNA
Methods used in the study RT-PCR
Western blotting
RatRef-12 Microarray
FACS
Mass spectrometry [MALDI TOF]
2
Experiment ID 93
ISEV standards
EM
EV Biophysical techniques
HSP70|GAPDH
EV Cytosolic markers
CD9|CD151
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 20124479    
Organism Rattus norvegicus
Experiment description Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Authors Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M, Lochnit G, Preissner KT, Zoller M.
Journal name CR
Publication year 2010
Sample Pancreatic cancer cells
Sample name AS-Tspan8
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14-1.17 g/mL
Molecules identified in the study Protein
mRNA
Methods used in the study RT-PCR
Western blotting
 Protein-protein interactions for RGD1561212
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which RGD1561212 is involved
No pathways found





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