Gene description for WASF2
Gene name WAS protein family, member 2
Gene symbol WASF2
Other names/aliases -
Species Bos taurus
 Database cross references - WASF2
ExoCarta ExoCarta_504482
Entrez Gene 504482
UniProt A2VDK6  
 WASF2 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for WASF2
Molecular Function
    actin binding GO:0003779 IEA
    protein complex binding GO:0032403 IEA
Biological Process
    actin cytoskeleton organization GO:0030036 IEA
    megakaryocyte development GO:0035855 IEA
    negative regulation of stress fiber assembly GO:0051497 IEA
    lamellipodium morphogenesis GO:0072673 IEA
    angiogenesis GO:0001525 IEA
    Rac protein signal transduction GO:0016601 IEA
    lamellipodium assembly GO:0030032 IEA
    endocytosis GO:0006897 IEA
    actin filament-based movement GO:0030048 IEA
    ameboidal-type cell migration GO:0001667 IEA
    positive regulation of lamellipodium assembly GO:0010592 IEA
Subcellular Localization
    early endosome GO:0005769 IEA
    cell-cell junction GO:0005911 IEA
    extracellular exosome GO:0070062 IEA
    lamellipodium GO:0030027 IEA
    SCAR complex GO:0031209 IEA
    ruffle GO:0001726 IEA
    cytoskeleton GO:0005856 IEA
 Experiment description of studies that identified WASF2 in exosomes
1
Experiment ID 213
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for WASF2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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