Gene description for CAP1
Gene name CAP, adenylate cyclase-associated protein 1 (yeast)
Gene symbol CAP1
Other names/aliases -
Species Bos taurus
 Database cross references - CAP1
ExoCarta ExoCarta_504519
Entrez Gene 504519
UniProt Q3SYV4  
 CAP1 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for CAP1
Molecular Function
    actin binding GO:0003779 IEA
Biological Process
    receptor-mediated endocytosis GO:0006898 IEA
    cell morphogenesis GO:0000902 IEA
    actin cytoskeleton organization GO:0030036 IEA
    ameboidal-type cell migration GO:0001667 IEA
Subcellular Localization
    extracellular exosome GO:0070062 IEA
    focal adhesion GO:0005925 IEA
    plasma membrane GO:0005886 IEA
    cortical actin cytoskeleton GO:0030864 IEA
 Experiment description of studies that identified CAP1 in exosomes
1
Experiment ID 213
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for CAP1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which CAP1 is involved
PathwayEvidenceSource
Platelet degranulation IEA Reactome
Role of Abl in Robo-Slit signaling IEA Reactome





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