Gene description for ZPR1
Gene name ZPR1 zinc finger
Gene symbol ZPR1
Other names/aliases ZNF259
Species Bos taurus
 Database cross references - ZPR1
ExoCarta ExoCarta_504523
Entrez Gene 504523
UniProt Q2TBX0  
 ZPR1 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for ZPR1
Molecular Function
    receptor tyrosine kinase binding GO:0030971 IEA
    zinc ion binding GO:0008270 IEA
    translation initiation factor binding GO:0031369 IEA
Biological Process
    RNA splicing GO:0008380 IEA
    negative regulation of motor neuron apoptotic process GO:2000672 ISS
    inner cell mass cell proliferation GO:0001833 IEA
    positive regulation of transcription involved in G1/S transition of mitotic cell cycle GO:0071931 ISS
    spinal cord development GO:0021510 ISS
    positive regulation of growth GO:0045927 ISS
    mRNA processing GO:0006397 IEA
    apoptotic process involved in development GO:1902742 ISS
    pre-mRNA catabolic process GO:1990261 ISS
    axon development GO:0061564 ISS
    Cajal body organization GO:0030576 ISS
    positive regulation of gene expression GO:0010628 ISS
    microtubule cytoskeleton organization GO:0000226 ISS
    trophectodermal cell proliferation GO:0001834 ISS
    positive regulation of RNA splicing GO:0033120 ISS
    positive regulation of protein import into nucleus GO:0042307 ISS
    DNA endoreduplication GO:0042023 ISS
    regulation of myelination GO:0031641 ISS
    cellular response to epidermal growth factor stimulus GO:0071364 ISS
Subcellular Localization
    growth cone GO:0030426 ISS
    nucleolus GO:0005730 ISS
    Gemini of coiled bodies GO:0097504 ISS
    Cajal body GO:0015030 ISS
    cytoplasm GO:0005737 ISS
    neuronal cell body GO:0043025 ISS
    perinuclear region of cytoplasm GO:0048471 IEA
    axon GO:0030424 ISS
    nucleus GO:0005634 ISS
    perikaryon GO:0043204 ISS
    nucleoplasm GO:0005654 ISS
    SMN complex GO:0032797 ISS
 Experiment description of studies that identified ZPR1 in exosomes
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ZPR1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which ZPR1 is involved
No pathways found

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