Gene description for COLEC12
Gene name collectin sub-family member 12
Gene symbol COLEC12
Other names/aliases -
Species Bos taurus
 Database cross references - COLEC12
ExoCarta ExoCarta_504741
Entrez Gene 504741
UniProt A6QP79  
 COLEC12 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for COLEC12
Molecular Function
    low-density lipoprotein particle binding GO:0030169 ISS
    signaling pattern recognition receptor activity GO:0008329 ISS
    carbohydrate binding GO:0030246 IEA
    metal ion binding GO:0046872 IEA
Biological Process
    immune response GO:0006955 IEA
    phagocytosis, recognition GO:0006910 ISS
    pattern recognition receptor signaling pathway GO:0002221 IEA
Subcellular Localization
    integral component of membrane GO:0016021 IEA
    extracellular exosome GO:0070062 IEA
    collagen trimer GO:0005581 IEA
 Experiment description of studies that identified COLEC12 in exosomes
1
Experiment ID 213
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for COLEC12
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which COLEC12 is involved
PathwayEvidenceSource
Scavenging by Class A Receptors IEA Reactome





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