Gene description for EIF4A1
Gene name eukaryotic translation initiation factor 4A1
Gene symbol EIF4A1
Other names/aliases -
Species Bos taurus
 Database cross references - EIF4A1
ExoCarta ExoCarta_504958
Entrez Gene 504958
UniProt Q3SZ54  
 EIF4A1 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for EIF4A1
Molecular Function
    ATP binding GO:0005524 IEA
    translation initiation factor activity GO:0003743 IEA
    poly(A) RNA binding GO:0044822 IEA
    double-stranded RNA binding GO:0003725 IEA
    ATP-dependent RNA helicase activity GO:0004004 IBA
Biological Process
    RNA secondary structure unwinding GO:0010501 IBA
    translational initiation GO:0006413 IBA
    regulation of gene expression GO:0010468 IBA
Subcellular Localization
    extracellular exosome GO:0070062 IEA
    membrane GO:0016020 IEA
 Experiment description of studies that identified EIF4A1 in exosomes
1
Experiment ID 213
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for EIF4A1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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