Gene description for EIF4A1
Gene name eukaryotic translation initiation factor 4A1
Gene symbol EIF4A1
Other names/aliases -
Species Bos taurus
 Database cross references - EIF4A1
ExoCarta ExoCarta_504958
Entrez Gene 504958
UniProt Q3SZ54  
 EIF4A1 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for EIF4A1
Molecular Function
    ATP binding GO:0005524 IEA
    translation initiation factor activity GO:0003743 IEA
    poly(A) RNA binding GO:0044822 IEA
    double-stranded RNA binding GO:0003725 IEA
    ATP-dependent RNA helicase activity GO:0004004 IBA
Biological Process
    RNA secondary structure unwinding GO:0010501 IBA
    translational initiation GO:0006413 IBA
    regulation of gene expression GO:0010468 IBA
Subcellular Localization
    extracellular exosome GO:0070062 IEA
    membrane GO:0016020 IEA
 Experiment description of studies that identified EIF4A1 in exosomes
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for EIF4A1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.

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