Gene description for CASP8AP2
Gene name caspase 8 associated protein 2
Gene symbol CASP8AP2
Other names/aliases -
Species Bos taurus
 Database cross references - CASP8AP2
ExoCarta ExoCarta_505138
Vesiclepedia VP_505138
Entrez Gene 505138
 CASP8AP2 identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for CASP8AP2
Molecular Function
    transcription corepressor activity GO:0003714 IEA
Biological Process
    extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 IEA
    Fas signaling pathway GO:0036337 IEA
Subcellular Localization
    mitochondrion GO:0005739 IEA
    PML body GO:0016605 IEA
 Experiment description of studies that identified CASP8AP2 in sEVs
1
Experiment ID 213
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for CASP8AP2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which CASP8AP2 is involved
No pathways found





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