Gene description for MAP3K13
Gene name mitogen-activated protein kinase kinase kinase 13
Gene symbol MAP3K13
Other names/aliases -
Species Bos taurus
 Database cross references - MAP3K13
ExoCarta ExoCarta_505369
Entrez Gene 505369
UniProt A7MBB4  
 MAP3K13 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for MAP3K13
Molecular Function
    MAP kinase kinase kinase activity GO:0004709 IEA
    metal ion binding GO:0046872 IEA
    ATP binding GO:0005524 IEA
    protein homodimerization activity GO:0042803 IEA
Biological Process
    activation of MAPKK activity GO:0000186 IEA
    protein autophosphorylation GO:0046777 IEA
    positive regulation of NF-kappaB transcription factor activity GO:0051092 IEA
    JNK cascade GO:0007254 IEA
Subcellular Localization
    cytoplasm GO:0005737 IEA
    membrane GO:0016020 IEA
 Experiment description of studies that identified MAP3K13 in exosomes
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for MAP3K13
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which MAP3K13 is involved
No pathways found

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