Gene description for APOA2
Gene name apolipoprotein A-II
Gene symbol APOA2
Other names/aliases -
Species Bos taurus
 Database cross references - APOA2
ExoCarta ExoCarta_505394
Vesiclepedia VP_505394
Entrez Gene 505394
UniProt P81644  
 APOA2 identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for APOA2
Molecular Function
    high-density lipoprotein particle binding GO:0008035 IEA
    cholesterol binding GO:0015485 IEA
    phosphatidylcholine binding GO:0031210 IEA
    apolipoprotein receptor binding GO:0034190 IEA
    lipase inhibitor activity GO:0055102 IEA
    high-density lipoprotein particle receptor binding GO:0070653 IEA
Biological Process
    cholesterol metabolic process GO:0008203 IEA
    cholesterol transport GO:0030301 IEA
    triglyceride-rich lipoprotein particle remodeling GO:0034370 IEA
    low-density lipoprotein particle remodeling GO:0034374 IEA
    high-density lipoprotein particle remodeling GO:0034375 IEA
    high-density lipoprotein particle assembly GO:0034380 IEA
    lipoprotein metabolic process GO:0042157 IEA
    cholesterol homeostasis GO:0042632 IEA
    negative regulation of lipase activity GO:0060192 IEA
Subcellular Localization
    extracellular region GO:0005576 IEA
    very-low-density lipoprotein particle GO:0034361 IEA
    spherical high-density lipoprotein particle GO:0034366 IEA
    chylomicron GO:0042627 IEA
    blood microparticle GO:0072562 IEA
 Experiment description of studies that identified APOA2 in sEVs
1
Experiment ID 213
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for APOA2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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