Gene description for PYGL
Gene name phosphorylase, glycogen, liver
Gene symbol PYGL
Other names/aliases -
Species Bos taurus
 Database cross references - PYGL
ExoCarta ExoCarta_505472
Entrez Gene 505472
UniProt Q0VCM4  
 PYGL identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for PYGL
Molecular Function
    AMP binding GO:0016208 IEA
    pyridoxal phosphate binding GO:0030170 IBA
    purine nucleobase binding GO:0002060 IEA
    drug binding GO:0008144 IEA
    ATP binding GO:0005524 IEA
    vitamin binding GO:0019842 IEA
    glycogen phosphorylase activity GO:0008184 IBA
    bile acid binding GO:0032052 IEA
Biological Process
    necroptotic process GO:0070266 IEA
    glycogen catabolic process GO:0005980 IBA
    glucose homeostasis GO:0042593 IEA
Subcellular Localization
    cytoplasm GO:0005737 IBA
    extracellular exosome GO:0070062 IEA
    plasma membrane GO:0005886 IEA
 Experiment description of studies that identified PYGL in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PYGL
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which PYGL is involved
PathwayEvidenceSource
Glycogen breakdown (glycogenolysis) IEA Reactome





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