Gene description for ADH5
Gene name alcohol dehydrogenase 5 (class III), chi polypeptide
Gene symbol ADH5
Other names/aliases -
Species Bos taurus
 Database cross references - ADH5
ExoCarta ExoCarta_505515
Entrez Gene 505515
UniProt Q3ZC42  
 ADH5 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for ADH5
Molecular Function
    alcohol dehydrogenase (NAD) activity GO:0004022 IEA
    protein homodimerization activity GO:0042803 IEA
    S-(hydroxymethyl)glutathione dehydrogenase activity GO:0051903 IEA
    formaldehyde dehydrogenase activity GO:0018467 IEA
    zinc ion binding GO:0008270 IEA
    fatty acid binding GO:0005504 IEA
Biological Process
    response to nitrosative stress GO:0051409 IEA
    positive regulation of blood pressure GO:0045777 IEA
    retinoid metabolic process GO:0001523 IEA
    formaldehyde catabolic process GO:0046294 IEA
    ethanol oxidation GO:0006069 IEA
    response to redox state GO:0051775 IEA
    respiratory system process GO:0003016 IEA
    response to lipopolysaccharide GO:0032496 IEA
    peptidyl-cysteine S-nitrosylation GO:0018119 IEA
Subcellular Localization
    extracellular exosome GO:0070062 IEA
    mitochondrion GO:0005739 IEA
 Experiment description of studies that identified ADH5 in exosomes
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ADH5
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which ADH5 is involved
No pathways found

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