Gene description for Acot1
Gene name acyl-CoA thioesterase 1
Gene symbol Acot1
Other names/aliases Cte1
Species Rattus norvegicus
 Database cross references - Acot1
ExoCarta ExoCarta_50559
Entrez Gene 50559
UniProt O88267  
 Acot1 identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Acot1
Molecular Function
    palmitoyl-CoA hydrolase activity GO:0016290 IEA
    thiolester hydrolase activity GO:0016790 IEA
    carboxylic ester hydrolase activity GO:0052689 IEA
    acyl-CoA hydrolase activity GO:0047617 IDA
Biological Process
    acyl-CoA metabolic process GO:0006637 IEA
    lipid metabolic process GO:0006629 TAS
Subcellular Localization
    cytosol GO:0005829 IDA
 Experiment description of studies that identified Acot1 in exosomes
1
Experiment ID 225
ISEV standards
EM
EV Biophysical techniques
GAPDH
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Acot1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Acot1 is involved
No pathways found





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