Gene description for Acot1
Gene name acyl-CoA thioesterase 1
Gene symbol Acot1
Other names/aliases Cte1
Species Rattus norvegicus
 Database cross references - Acot1
ExoCarta ExoCarta_50559
Vesiclepedia VP_50559
Entrez Gene 50559
UniProt O88267  
 Acot1 identified in sEVs derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Acot1
Molecular Function
    thiolester hydrolase activity GO:0016790 IEA
    fatty acyl-CoA hydrolase activity GO:0047617 IBA
    fatty acyl-CoA hydrolase activity GO:0047617 IDA
    fatty acyl-CoA hydrolase activity GO:0047617 ISO
    carboxylic ester hydrolase activity GO:0052689 IEA
Biological Process
    very long-chain fatty acid metabolic process GO:0000038 ISO
    long-chain fatty acid metabolic process GO:0001676 IDA
    long-chain fatty acid metabolic process GO:0001676 ISO
    long-chain fatty acid metabolic process GO:0001676 ISO
    fatty acid metabolic process GO:0006631 IBA
    fatty acid metabolic process GO:0006631 IEA
    acyl-CoA metabolic process GO:0006637 IBA
    acyl-CoA metabolic process GO:0006637 IEA
    acyl-CoA metabolic process GO:0006637 ISO
    negative regulation of cardiac muscle cell apoptotic process GO:0010667 IMP
Subcellular Localization
    mitochondrion GO:0005739 ISO
    cytosol GO:0005829 ISO
 Experiment description of studies that identified Acot1 in sEVs
1
Experiment ID 225
MISEV standards
EM
Biophysical techniques
GAPDH|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors "Lee JE, Moon PG, Lee IK, Baek MC"
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Acot1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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