Gene description for Slco1a1
Gene name solute carrier organic anion transporter family, member 1a1
Gene symbol Slco1a1
Other names/aliases OATP-1
Oatp1
Slc21a1
Slc21a3
Species Rattus norvegicus
 Database cross references - Slco1a1
ExoCarta ExoCarta_50572
Entrez Gene 50572
UniProt P46720  
 Slco1a1 identified in exosomes derived from the following tissue/cell type
Urine 20535238    
 Gene ontology annotations for Slco1a1
Molecular Function
    organic anion transmembrane transporter activity GO:0008514 TAS
Biological Process
    organic anion transport GO:0015711 TAS
    response to stilbenoid GO:0035634 IEA
    response to testosterone GO:0033574 IEP
    activation of mitophagy in response to mitochondrial depolarization GO:0098779 ISO
Subcellular Localization
    basolateral plasma membrane GO:0016323 IEA
    integral component of plasma membrane GO:0005887 TAS
 Experiment description of studies that identified Slco1a1 in exosomes
1
Experiment ID 192
ISEV standards
✔
CEM
EV Biophysical techniques
✔
TSG101|HSP70
EV Cytosolic markers
✔
CD63|CD81|FLOT
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20535238    
Organism Rattus norvegicus
Experiment description Candidate biomarkers in exosome-like vesicles purified from rat and mouse urine samples.
Authors Conde-Vancells J, Rodriguez-Suarez E, Gonzalez E, Berisa A, Gil D, Embade N, Valle M, Luka Z, Elortza F, Wagner C, Lu SC, Mato JM, Falcon-Perez M.
Journal name Proteomics Clin Appl
Publication year 2010
Sample Urine
Sample name Urine - Rats of liver injury
Isolation/purification methods Differential centrifugation
Filtration
UltracentrifugationSucrose cushion
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Slco1a1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Slco1a1 is involved
PathwayEvidenceSource
Recycling of bile acids and salts IEA Reactome
Transport of organic anions IEA Reactome





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