Gene description for Slco1a1
Gene name solute carrier organic anion transporter family, member 1a1
Gene symbol Slco1a1
Other names/aliases OATP-1
Oatp1
Slc21a1
Slc21a3
Species Rattus norvegicus
 Database cross references - Slco1a1
ExoCarta ExoCarta_50572
Vesiclepedia VP_50572
Entrez Gene 50572
UniProt P46720  
 Slco1a1 identified in sEVs derived from the following tissue/cell type
Urine 20535238    
 Gene ontology annotations for Slco1a1
Molecular Function
    organic anion transmembrane transporter activity GO:0008514 IDA
    organic anion transmembrane transporter activity GO:0008514 TAS
    bile acid transmembrane transporter activity GO:0015125 IBA
    sodium-independent organic anion transmembrane transporter activity GO:0015347 IBA
    transmembrane transporter activity GO:0022857 IEA
Biological Process
    monoatomic ion transport GO:0006811 IEA
    organic anion transport GO:0015711 IEP
    organic anion transport GO:0015711 TAS
    bile acid and bile salt transport GO:0015721 IBA
    response to testosterone GO:0033574 IEP
    response to stilbenoid GO:0035634 IEA
    sodium-independent organic anion transport GO:0043252 IBA
    transmembrane transport GO:0055085 IEA
Subcellular Localization
    plasma membrane GO:0005886 IEA
    basolateral plasma membrane GO:0016323 IBA
 Experiment description of studies that identified Slco1a1 in sEVs
1
Experiment ID 192
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|HSP70|CD63|CD81|FLOT
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20535238    
Organism Rattus norvegicus
Experiment description Candidate biomarkers in exosome-like vesicles purified from rat and mouse urine samples.
Authors "Conde-Vancells J, Rodriguez-Suarez E, Gonzalez E, Berisa A, Gil D, Embade N, Valle M, Luka Z, Elortza F, Wagner C, Lu SC, Mato JM, Falcon-Perez M."
Journal name Proteomics Clin Appl
Publication year 2010
Sample Urine
Sample name Urine - Rats of liver injury
Isolation/purification methods Differential centrifugation
Filtration
UltracentrifugationSucrose cushion
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Slco1a1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Slco1a1 is involved
No pathways found





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