Gene description for SLC16A1
Gene name solute carrier family 16 (monocarboxylate transporter), member 1
Gene symbol SLC16A1
Other names/aliases MCT1
Species Bos taurus
 Database cross references - SLC16A1
ExoCarta ExoCarta_505775
Entrez Gene 505775
UniProt Q3MHW6  
 SLC16A1 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for SLC16A1
Molecular Function
    symporter activity GO:0015293 IEA
    lactate transmembrane transporter activity GO:0015129 IBA
Biological Process
    lipid metabolic process GO:0006629 IEA
    glucose homeostasis GO:0042593 IEA
    plasma membrane lactate transport GO:0035879 ISS
    behavioral response to nutrient GO:0051780 IEA
    regulation of insulin secretion GO:0050796 IEA
    response to food GO:0032094 IEA
    centrosome organization GO:0051297 IEA
Subcellular Localization
    plasma membrane GO:0005886 ISS
    extracellular exosome GO:0070062 IEA
    integral component of plasma membrane GO:0005887 ISS
    mitochondrion GO:0005739 IEA
    centrosome GO:0005813 IEA
 Experiment description of studies that identified SLC16A1 in exosomes
1
Experiment ID 213
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for SLC16A1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which SLC16A1 is involved
PathwayEvidenceSource
Basigin interactions IEA Reactome
Proton-coupled monocarboxylate transport IEA Reactome
Pyruvate metabolism IEA Reactome





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