Gene description for SLC16A1
Gene name solute carrier family 16 (monocarboxylate transporter), member 1
Gene symbol SLC16A1
Other names/aliases MCT1
Species Bos taurus
 Database cross references - SLC16A1
ExoCarta ExoCarta_505775
Entrez Gene 505775
UniProt Q3MHW6  
 SLC16A1 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for SLC16A1
Molecular Function
    symporter activity GO:0015293 IEA
    lactate transmembrane transporter activity GO:0015129 IBA
Biological Process
    lipid metabolic process GO:0006629 IEA
    glucose homeostasis GO:0042593 IEA
    plasma membrane lactate transport GO:0035879 ISS
    behavioral response to nutrient GO:0051780 IEA
    regulation of insulin secretion GO:0050796 IEA
    response to food GO:0032094 IEA
    centrosome organization GO:0051297 IEA
Subcellular Localization
    plasma membrane GO:0005886 ISS
    extracellular exosome GO:0070062 IEA
    integral component of plasma membrane GO:0005887 ISS
    mitochondrion GO:0005739 IEA
    centrosome GO:0005813 IEA
 Experiment description of studies that identified SLC16A1 in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for SLC16A1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which SLC16A1 is involved
PathwayEvidenceSource
Basigin interactions IEA Reactome
Proton-coupled monocarboxylate transport IEA Reactome
Pyruvate metabolism IEA Reactome





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