Gene description for MVK
Gene name mevalonate kinase
Gene symbol MVK
Other names/aliases -
Species Bos taurus
 Database cross references - MVK
ExoCarta ExoCarta_505792
Vesiclepedia VP_505792
Entrez Gene 505792
UniProt Q5E9T8  
 MVK identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for MVK
Molecular Function
    mevalonate kinase activity GO:0004496 IEA
    ATP binding GO:0005524 IEA
Biological Process
    cholesterol biosynthetic process GO:0006695 IEA
    isoprenoid biosynthetic process GO:0008299 IEA
Subcellular Localization
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified MVK in sEVs
1
Experiment ID 213
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for MVK
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which MVK is involved
PathwayEvidenceSource
Cholesterol biosynthesis IEA Reactome
Metabolism IEA Reactome
Metabolism of lipids IEA Reactome
Metabolism of steroids IEA Reactome





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