Gene description for AFP
Gene name alpha-fetoprotein
Gene symbol AFP
Other names/aliases -
Species Bos taurus
 Database cross references - AFP
ExoCarta ExoCarta_506011
Vesiclepedia VP_506011
Entrez Gene 506011
UniProt Q3SZ57  
 AFP identified in sEVs derived from the following tissue/cell type
Milk 23459212    
Serum 19327352    
 Gene ontology annotations for AFP
Molecular Function
    fatty acid binding GO:0005504 IEA
    zinc ion binding GO:0008270 IEA
Biological Process
    transport GO:0006810 IEA
Subcellular Localization
    extracellular space GO:0005615 IEA
    cytoplasm GO:0005737 IEA
    blood microparticle GO:0072562 IEA
 Experiment description of studies that identified AFP in sEVs
1
Experiment ID 213
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 187
MISEV standards
✔
EM
Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19327352    
Organism Bos taurus
Experiment description Anchorage-independent growth of breast carcinoma cells is mediated by serum exosomes.
Authors "Ochieng J, Pratap S, Khatua AK, Sakwe AM."
Journal name Exp Cell Res
Publication year 2009
Sample Serum
Sample name Normal - Fetal bovine serum
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for AFP
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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