Gene description for Slc23a1
Gene name solute carrier family 23 (ascorbic acid transporter), member 1
Gene symbol Slc23a1
Other names/aliases SVCT1
Species Rattus norvegicus
 Database cross references - Slc23a1
ExoCarta ExoCarta_50621
Vesiclepedia VP_50621
Entrez Gene 50621
UniProt Q9WTW7  
 Slc23a1 identified in exosomes derived from the following tissue/cell type
Urine 20535238    
 Gene ontology annotations for Slc23a1
Molecular Function
    L-ascorbate:sodium symporter activity GO:0008520 IDA
    L-ascorbate:sodium symporter activity GO:0008520 IEA
    L-ascorbate:sodium symporter activity GO:0008520 ISO
    L-ascorbate:sodium symporter activity GO:0008520 ISO
    L-ascorbate:sodium symporter activity GO:0008520 ISS
    sodium ion transmembrane transporter activity GO:0015081 ISO
    sodium ion transmembrane transporter activity GO:0015081 ISS
    urate transmembrane transporter activity GO:0015143 IEA
    urate transmembrane transporter activity GO:0015143 ISO
    urate transmembrane transporter activity GO:0015143 ISS
    L-ascorbic acid transmembrane transporter activity GO:0015229 IBA
    L-ascorbic acid transmembrane transporter activity GO:0015229 IDA
    L-ascorbic acid transmembrane transporter activity GO:0015229 IEA
    L-ascorbic acid transmembrane transporter activity GO:0015229 ISO
    dehydroascorbic acid transmembrane transporter activity GO:0033300 IEA
    dehydroascorbic acid transmembrane transporter activity GO:0033300 ISO
    dehydroascorbic acid transmembrane transporter activity GO:0033300 ISS
Biological Process
    sodium ion transport GO:0006814 ISO
    sodium ion transport GO:0006814 ISS
    brain development GO:0007420 IEA
    brain development GO:0007420 ISO
    brain development GO:0007420 ISS
    response to toxic substance GO:0009636 IEA
    response to toxic substance GO:0009636 ISO
    response to toxic substance GO:0009636 ISS
    urate transport GO:0015747 IEA
    L-ascorbic acid transmembrane transport GO:0015882 IDA
    L-ascorbic acid transmembrane transport GO:0015882 IEA
    L-ascorbic acid transmembrane transport GO:0015882 ISO
    L-ascorbic acid transmembrane transport GO:0015882 ISO
    lung development GO:0030324 IEA
    lung development GO:0030324 ISO
    sodium ion transmembrane transport GO:0035725 IEA
    dehydroascorbic acid transport GO:0070837 IEA
    dehydroascorbic acid transport GO:0070837 ISO
    dehydroascorbic acid transport GO:0070837 ISS
Subcellular Localization
    cytoplasm GO:0005737 IDA
    cytoplasm GO:0005737 IEA
    cytoplasm GO:0005737 ISO
    plasma membrane GO:0005886 ISO
    brush border GO:0005903 IDA
    basal plasma membrane GO:0009925 IDA
    basal plasma membrane GO:0009925 IEA
    basal plasma membrane GO:0009925 ISO
    apical plasma membrane GO:0016324 IBA
    apical plasma membrane GO:0016324 IEA
    apical plasma membrane GO:0016324 ISO
    apical plasma membrane GO:0016324 ISS
 Experiment description of studies that identified Slc23a1 in exosomes
1
Experiment ID 192
MISEV standards
CEM
Biophysical techniques
TSG101|HSP70|CD63|CD81|FLOT
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20535238    
Organism Rattus norvegicus
Experiment description Candidate biomarkers in exosome-like vesicles purified from rat and mouse urine samples.
Authors "Conde-Vancells J, Rodriguez-Suarez E, Gonzalez E, Berisa A, Gil D, Embade N, Valle M, Luka Z, Elortza F, Wagner C, Lu SC, Mato JM, Falcon-Perez M."
Journal name Proteomics Clin Appl
Publication year 2010
Sample Urine
Sample name Urine - Rats of liver injury
Isolation/purification methods Differential centrifugation
Filtration
UltracentrifugationSucrose cushion
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Slc23a1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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