Gene description for PDXP
Gene name pyridoxal (pyridoxine, vitamin B6) phosphatase
Gene symbol PDXP
Other names/aliases -
Species Bos taurus
 Database cross references - PDXP
ExoCarta ExoCarta_506308
Entrez Gene 506308
UniProt Q3ZBF9  
 PDXP identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for PDXP
Molecular Function
    phosphoprotein phosphatase activity GO:0004721 IDA
    magnesium ion binding GO:0000287 ISS
    phosphoserine phosphatase activity GO:0004647 IEA
    pyridoxal phosphatase activity GO:0033883 ISS
Biological Process
    positive regulation of actin filament depolymerization GO:0030836 ISS
    protein dephosphorylation GO:0006470 IDA
    pyridoxal phosphate catabolic process GO:0032361 ISS
    regulation of mitotic nuclear division GO:0007088 ISS
    regulation of cytokinesis GO:0032465 ISS
Subcellular Localization
    actin cytoskeleton GO:0015629 ISS
    cleavage furrow GO:0032154 ISS
    lamellipodium GO:0030027 ISS
    contractile ring GO:0070938 ISS
    midbody GO:0030496 ISS
    lamellipodium membrane GO:0031258 IEA
    plasma membrane GO:0005886 ISS
    ruffle membrane GO:0032587 ISS
    cytosol GO:0005829 IDA
 Experiment description of studies that identified PDXP in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PDXP
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which PDXP is involved
No pathways found





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