Gene description for RAB25
Gene name RAB25, member RAS oncogene family
Gene symbol RAB25
Other names/aliases -
Species Bos taurus
 Database cross references - RAB25
ExoCarta ExoCarta_506482
Entrez Gene 506482
UniProt Q58DW6  
 RAB25 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for RAB25
Molecular Function
    GTP binding GO:0005525 IEA
    myosin V binding GO:0031489 IEA
    GTPase activity GO:0003924 IBA
Biological Process
    Rab protein signal transduction GO:0032482 IBA
    positive regulation of epithelial cell migration GO:0010634 IEA
    positive regulation of cell proliferation GO:0008284 ISS
    melanosome transport GO:0032402 IBA
    epithelial cell morphogenesis GO:0003382 ISS
    pseudopodium organization GO:0031268 ISS
    exocytosis GO:0006887 IBA
    metabolic process GO:0008152 IBA
    regulation of vesicle-mediated transport GO:0060627 IEA
    intracellular protein transport GO:0006886 IBA
Subcellular Localization
    pseudopodium GO:0031143 ISS
    recycling endosome GO:0055037 IBA
    cytoplasmic membrane-bounded vesicle GO:0016023 IEA
    extracellular exosome GO:0070062 IEA
    pseudopodium membrane GO:0031260 IEA
    cytoplasmic vesicle GO:0031410 ISS
 Experiment description of studies that identified RAB25 in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for RAB25
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which RAB25 is involved
No pathways found





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