Gene description for CLP1
Gene name cleavage and polyadenylation factor I subunit 1
Gene symbol CLP1
Other names/aliases -
Species Bos taurus
 Database cross references - CLP1
ExoCarta ExoCarta_506507
Entrez Gene 506507
UniProt A2VE01  
 CLP1 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for CLP1
Molecular Function
    polydeoxyribonucleotide kinase activity GO:0051733 ISS
    ATP-dependent polyribonucleotide 5'-hydroxyl-kinase activity GO:0051736 ISS
    ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity GO:0046404 IEA
    polynucleotide 5'-hydroxyl-kinase activity GO:0051731 IBA
    ATP binding GO:0005524 IEA
Biological Process
    phosphorylation GO:0016310 IEA
    siRNA loading onto RISC involved in RNA interference GO:0035087 ISS
    tRNA splicing, via endonucleolytic cleavage and ligation GO:0006388 ISS
    mRNA cleavage GO:0006379 IBA
    cerebellar cortex development GO:0021695 ISS
    mRNA polyadenylation GO:0006378 IBA
    targeting of mRNA for destruction involved in RNA interference GO:0030423 ISS
Subcellular Localization
    mRNA cleavage factor complex GO:0005849 IEA
    nucleus GO:0005634 IBA
    tRNA-intron endonuclease complex GO:0000214 ISS
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified CLP1 in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for CLP1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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