Gene description for TWF1
Gene name twinfilin actin-binding protein 1
Gene symbol TWF1
Other names/aliases PTK9
Species Bos taurus
 Database cross references - TWF1
ExoCarta ExoCarta_506683
Entrez Gene 506683
UniProt Q56JV6  
 TWF1 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for TWF1
Molecular Function
    phosphatidylinositol-4,5-bisphosphate binding GO:0005546 IEA
    protein tyrosine kinase activity GO:0004713 IEA
    actin monomer binding GO:0003785 IEA
Biological Process
    peptidyl-tyrosine phosphorylation GO:0018108 IEA
    sequestering of actin monomers GO:0042989 IEA
    barbed-end actin filament capping GO:0051016 IEA
Subcellular Localization
    perinuclear region of cytoplasm GO:0048471 IEA
    ruffle membrane GO:0032587 IEA
    myofibril GO:0030016 IEA
    filopodium GO:0030175 IEA
    actin cytoskeleton GO:0015629 IEA
    cell-cell junction GO:0005911 IEA
 Experiment description of studies that identified TWF1 in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for TWF1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which TWF1 is involved
No pathways found





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