Gene description for LTA4H
Gene name leukotriene A4 hydrolase
Gene symbol LTA4H
Other names/aliases -
Species Bos taurus
 Database cross references - LTA4H
ExoCarta ExoCarta_507130
Vesiclepedia VP_507130
Entrez Gene 507130
UniProt Q3SZH7  
 LTA4H identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for LTA4H
Molecular Function
    aminopeptidase activity GO:0004177 IEA
    epoxide hydrolase activity GO:0004301 IEA
    leukotriene-A4 hydrolase activity GO:0004463 IEA
    metallopeptidase activity GO:0008237 IEA
    zinc ion binding GO:0008270 IEA
Biological Process
    proteolysis GO:0006508 IEA
    leukotriene biosynthetic process GO:0019370 IEA
    peptide catabolic process GO:0043171 IEA
Subcellular Localization
    nucleus GO:0005634 IEA
    cytosol GO:0005829 IEA
 Experiment description of studies that identified LTA4H in sEVs
1
Experiment ID 213
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for LTA4H
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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