Gene description for VCP
Gene name valosin containing protein
Gene symbol VCP
Other names/aliases p97
Species Bos taurus
 Database cross references - VCP
ExoCarta ExoCarta_507345
Vesiclepedia VP_507345
Entrez Gene 507345
UniProt Q3ZBT1  
 VCP identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for VCP
Molecular Function
    ATP binding GO:0005524 IEA
    ATP hydrolysis activity GO:0016887 IEA
    polyubiquitin modification-dependent protein binding GO:0031593 IEA
Biological Process
    retrograde protein transport, ER to cytosol GO:0030970 IEA
    mitotic spindle disassembly GO:0051228 IEA
    autophagosome maturation GO:0097352 IEA
Subcellular Localization
    nucleus GO:0005634 IEA
    cytosol GO:0005829 IEA
    VCP-NPL4-UFD1 AAA ATPase complex GO:0034098 IEA
 Experiment description of studies that identified VCP in exosomes
1
Experiment ID 213
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for VCP
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which VCP is involved
No pathways found





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