Gene description for PRPF8
Gene name pre-mRNA processing factor 8
Gene symbol PRPF8
Other names/aliases -
Species Bos taurus
 Database cross references - PRPF8
ExoCarta ExoCarta_507371
Vesiclepedia VP_507371
Entrez Gene 507371
 PRPF8 identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for PRPF8
Molecular Function
    protein binding GO:0005515 IEA
    metallopeptidase activity GO:0008237 IEA
    U6 snRNA binding GO:0017070 IEA
    U1 snRNA binding GO:0030619 IEA
    U2 snRNA binding GO:0030620 IEA
    U5 snRNA binding GO:0030623 IEA
    pre-mRNA intronic binding GO:0097157 IEA
Biological Process
    spliceosomal tri-snRNP complex assembly GO:0000244 IEA
    mRNA splicing, via spliceosome GO:0000398 IEA
Subcellular Localization
    U5 snRNP GO:0005682 IEA
    catalytic step 2 spliceosome GO:0071013 IEA
 Experiment description of studies that identified PRPF8 in sEVs
1
Experiment ID 213
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PRPF8
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which PRPF8 is involved
No pathways found





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