Gene description for VTN
Gene name vitronectin
Gene symbol VTN
Other names/aliases -
Species Bos taurus
 Database cross references - VTN
ExoCarta ExoCarta_507525
Vesiclepedia VP_507525
Entrez Gene 507525
 VTN identified in sEVs derived from the following tissue/cell type
Milk 23459212    
Serum 19327352    
 Gene ontology annotations for VTN
Molecular Function
    scavenger receptor activity GO:0005044 IEA
    polysaccharide binding GO:0030247 IEA
    extracellular matrix binding GO:0050840 IEA
Biological Process
    immune response GO:0006955 IEA
    cell-matrix adhesion GO:0007160 IEA
    cell adhesion mediated by integrin GO:0033627 IEA
Subcellular Localization
    extracellular space GO:0005615 IEA
    collagen-containing extracellular matrix GO:0062023 IEA
 Experiment description of studies that identified VTN in sEVs
1
Experiment ID 213
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 187
MISEV standards
EM
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19327352    
Organism Bos taurus
Experiment description Anchorage-independent growth of breast carcinoma cells is mediated by serum exosomes.
Authors "Ochieng J, Pratap S, Khatua AK, Sakwe AM."
Journal name Exp Cell Res
Publication year 2009
Sample Serum
Sample name Normal - Fetal bovine serum
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for VTN
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which VTN is involved
No pathways found





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