Gene description for HPN
Gene name hepsin
Gene symbol HPN
Other names/aliases -
Species Bos taurus
 Database cross references - HPN
ExoCarta ExoCarta_508148
Vesiclepedia VP_508148
Entrez Gene 508148
 HPN identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for HPN
Molecular Function
    serine-type endopeptidase activity GO:0004252 IEA
    serine-type exopeptidase activity GO:0070008 IEA
Biological Process
    proteolysis GO:0006508 IEA
    regulation of cell shape GO:0008360 IEA
    negative regulation of epithelial to mesenchymal transition GO:0010719 IEA
Subcellular Localization
    membrane GO:0016020 IEA
 Experiment description of studies that identified HPN in sEVs
1
Experiment ID 213
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for HPN
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which HPN is involved
No pathways found





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