Gene description for AHCY
Gene name adenosylhomocysteinase
Gene symbol AHCY
Other names/aliases -
Species Bos taurus
 Database cross references - AHCY
ExoCarta ExoCarta_508158
Entrez Gene 508158
UniProt Q3MHL4  
 AHCY identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for AHCY
Molecular Function
    adenosylhomocysteinase activity GO:0004013 IBA
Biological Process
    S-adenosylmethionine cycle GO:0033353 IBA
    one-carbon metabolic process GO:0006730 IEA
Subcellular Localization
    cytosol GO:0005829 ISS
    melanosome GO:0042470 IEA
    extracellular exosome GO:0070062 IEA
 Experiment description of studies that identified AHCY in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for AHCY
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which AHCY is involved
PathwayEvidenceSource
Methylation IEA Reactome
Sulfur amino acid metabolism IEA Reactome





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here