Gene description for ITIH3
Gene name inter-alpha-trypsin inhibitor heavy chain 3
Gene symbol ITIH3
Other names/aliases -
Species Bos taurus
 Database cross references - ITIH3
ExoCarta ExoCarta_508355
Entrez Gene 508355
UniProt P56652  
 ITIH3 identified in exosomes derived from the following tissue/cell type
Serum 19327352    
 Gene ontology annotations for ITIH3
Molecular Function
    serine-type endopeptidase inhibitor activity GO:0004867 IEA
Biological Process
    negative regulation of endopeptidase activity GO:0010951 IEA
    hyaluronan metabolic process GO:0030212 IEA
Subcellular Localization
    extracellular exosome GO:0070062 IEA
 Experiment description of studies that identified ITIH3 in exosomes
1
Experiment ID 187
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19327352    
Organism Bos taurus
Experiment description Anchorage-independent growth of breast carcinoma cells is mediated by serum exosomes.
Authors Ochieng J, Pratap S, Khatua AK, Sakwe AM.
Journal name Exp Cell Res
Publication year 2009
Sample Serum
Sample name Normal - Fetal bovine serum
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ITIH3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which ITIH3 is involved
No pathways found





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