Gene description for DHX58
Gene name DEXH (Asp-Glu-X-His) box polypeptide 58
Gene symbol DHX58
Other names/aliases LGP2
Species Bos taurus
 Database cross references - DHX58
ExoCarta ExoCarta_508378
Vesiclepedia VP_508378
Entrez Gene 508378
 DHX58 identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for DHX58
Molecular Function
    DNA binding GO:0003677 IEA
    double-stranded RNA binding GO:0003725 IEA
    single-stranded RNA binding GO:0003727 IEA
    ATP binding GO:0005524 IEA
    zinc ion binding GO:0008270 IEA
    hydrolase activity GO:0016787 IEA
Biological Process
    response to virus GO:0009615 IEA
    positive regulation of interferon-beta production GO:0032728 IEA
    innate immune response GO:0045087 IEA
Subcellular Localization
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified DHX58 in sEVs
1
Experiment ID 213
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for DHX58
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which DHX58 is involved
No pathways found





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