Gene description for PFKL
Gene name phosphofructokinase, liver
Gene symbol PFKL
Other names/aliases ATP-PFK
PFK-L
Species Bos taurus
 Database cross references - PFKL
ExoCarta ExoCarta_508683
Vesiclepedia VP_508683
Entrez Gene 508683
UniProt A1A4J1  
 PFKL identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for PFKL
Molecular Function
    6-phosphofructokinase activity GO:0003872 IEA
    ATP binding GO:0005524 IEA
    AMP binding GO:0016208 IEA
    identical protein binding GO:0042802 IEA
    monosaccharide binding GO:0048029 IEA
    fructose-6-phosphate binding GO:0070095 IEA
Biological Process
    fructose 6-phosphate metabolic process GO:0006002 IEA
    fructose 1,6-bisphosphate metabolic process GO:0030388 IEA
    canonical glycolysis GO:0061621 IEA
Subcellular Localization
    cytoplasm GO:0005737 IEA
    6-phosphofructokinase complex GO:0005945 IEA
    membrane GO:0016020 IEA
 Experiment description of studies that identified PFKL in sEVs
1
Experiment ID 213
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PFKL
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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