Gene description for OTULIN
Gene name OTU deubiquitinase with linear linkage specificity
Gene symbol OTULIN
Other names/aliases FAM105B
Species Bos taurus
 Database cross references - OTULIN
ExoCarta ExoCarta_508963
Vesiclepedia VP_508963
Entrez Gene 508963
 OTULIN identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for OTULIN
Molecular Function
    cysteine-type deubiquitinase activity GO:0004843 IEA
Biological Process
    protein linear deubiquitination GO:1990108 IEA
 Experiment description of studies that identified OTULIN in sEVs
1
Experiment ID 213
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for OTULIN
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which OTULIN is involved
No pathways found





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