Gene description for PDCD5
Gene name programmed cell death 5
Gene symbol PDCD5
Other names/aliases TFAR19
Species Bos taurus
 Database cross references - PDCD5
ExoCarta ExoCarta_509123
Entrez Gene 509123
UniProt Q2HJH9  
 PDCD5 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for PDCD5
Molecular Function
    beta-tubulin binding GO:0048487 IEA
    acetyltransferase activator activity GO:0010698 IEA
    DNA binding GO:0003677 IEA
    heparin binding GO:0008201 IEA
Biological Process
    positive regulation of gene expression GO:0010628 IEA
    negative regulation of chaperone-mediated protein folding GO:1903645 IEA
    cellular response to transforming growth factor beta stimulus GO:0071560 IEA
    negative regulation of cell proliferation GO:0008285 IEA
    positive regulation of release of cytochrome c from mitochondria GO:0090200 IEA
    positive regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043280 IEA
    positive regulation of protein import into mitochondrial outer membrane GO:1903638 IEA
Subcellular Localization
    nucleus GO:0005634 IEA
    extracellular exosome GO:0070062 IEA
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified PDCD5 in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PDCD5
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which PDCD5 is involved
No pathways found





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