Gene description for Klrg1
Gene name killer cell lectin-like receptor subfamily G, member 1
Gene symbol Klrg1
Other names/aliases 2F1-Ag
MAFA
MAFA-L
Species Mus musculus
 Database cross references - Klrg1
ExoCarta ExoCarta_50928
Entrez Gene 50928
UniProt O88713  
 Klrg1 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Klrg1
Molecular Function
    carbohydrate binding GO:0030246 TAS
Biological Process
    innate immune response GO:0045087 IEA
    cell surface receptor signaling pathway GO:0007166 TAS
    immune system process GO:0002376 IEA
Subcellular Localization
    integral component of membrane GO:0016021 IEA
    membrane GO:0016020 IEA
    plasma membrane GO:0005886 IEA
 Experiment description of studies that identified Klrg1 in exosomes
1
Experiment ID 15
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Klrg1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Klrg1 is involved
PathwayEvidenceSource
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell IEA Reactome





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