Gene description for UBA5
Gene name ubiquitin-like modifier activating enzyme 5
Gene symbol UBA5
Other names/aliases -
Species Bos taurus
 Database cross references - UBA5
ExoCarta ExoCarta_509292
Entrez Gene 509292
UniProt A7MAZ3  
 UBA5 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for UBA5
Molecular Function
    UFM1 activating enzyme activity GO:0071566 ISS
    ATP binding GO:0005524 IEA
    metal ion binding GO:0046872 IEA
Biological Process
    response to endoplasmic reticulum stress GO:0034976 IEA
    regulation of intracellular estrogen receptor signaling pathway GO:0033146 ISS
    protein ufmylation GO:0071569 ISS
    protein K69-linked ufmylation GO:1990592 ISS
Subcellular Localization
    cytosol GO:0005829 IBA
    nucleus GO:0005634 IEA
 Experiment description of studies that identified UBA5 in exosomes
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for UBA5
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which UBA5 is involved
Antigen processing: Ubiquitination & Proteasome degradation IEA Reactome

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