Gene description for PCBP1
Gene name poly(rC) binding protein 1
Gene symbol PCBP1
Other names/aliases HEL-S-85
HNRPE1
HNRPX
hnRNP-E1
hnRNP-X
Species Homo sapiens
 Database cross references - PCBP1
ExoCarta ExoCarta_5093
Vesiclepedia VP_5093
Entrez Gene 5093
HGNC 8647
MIM 601209
UniProt Q15365  
 PCBP1 identified in sEVs derived from the following tissue/cell type
B cells 20458337    
B cells 20458337    
B cells 20458337    
Bladder cancer cells 20224111    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 35918900    
Breast cancer cells 35918900    
Chondrocytes 35931686    
Chondrocytes 35931686    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 17956143    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 25890246    
Colorectal cancer cells 34887515    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Endothelial cells 26027894    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Hepatocellular carcinoma cells 26054723    
Hepatocellular carcinoma cells 26054723    
Hepatocellular carcinoma cells 26054723    
Hepatocytes 26054723    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Nasopharyngeal carcinoma cells 25857718    
Nasopharyngeal carcinoma cells 25857718    
Nasopharyngeal carcinoma cells 25857718    
Neuroblastoma cells 25944692    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Platelets 25332113    
Platelets 25332113    
Platelets 25332113    
Pluripotent stem cells 34108659    
Prostate cancer cells 25844599    
Prostate cancer cells 25844599    
Squamous carcinoma cells 20124223    
T lymphocytes 34108659    
Thymus 23844026    
Urine 19056867    
 Gene ontology annotations for PCBP1
Molecular Function
    DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 IEA
    single-stranded DNA binding GO:0003697 IBA
    single-stranded DNA binding GO:0003697 IDA
    RNA binding GO:0003723 HDA
    RNA binding GO:0003723 IDA
    mRNA binding GO:0003729 IBA
    mRNA binding GO:0003729 IDA
    protein binding GO:0005515 IPI
    cadherin binding GO:0045296 HDA
    sequence-specific single stranded DNA binding GO:0098847 IEA
Biological Process
    viral RNA genome replication GO:0039694 IDA
    positive regulation of transcription by RNA polymerase II GO:0045944 IBA
Subcellular Localization
    nucleus GO:0005634 IBA
    nucleoplasm GO:0005654 IBA
    nucleoplasm GO:0005654 IDA
    nucleoplasm GO:0005654 TAS
    cytoplasm GO:0005737 IBA
    cytoplasm GO:0005737 IDA
    cytosol GO:0005829 IDA
    postsynaptic density GO:0014069 IEA
    membrane GO:0016020 HDA
    nuclear speck GO:0016607 IDA
    cytoplasmic ribonucleoprotein granule GO:0036464 IDA
    extracellular exosome GO:0070062 HDA
    ribonucleoprotein complex GO:1990904 IEA
 Experiment description of studies that identified PCBP1 in sEVs
1
Experiment ID 79
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 1
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
2
Experiment ID 80
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis -Sample 2
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
3
Experiment ID 81
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 3
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
4
Experiment ID 76
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|GAPDH|HSP90|CD81|CD9|CD63|LAMP1|MHCI
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20224111    
Organism Homo sapiens
Experiment description Proteomics analysis of bladder cancer exosomes.
Authors "Welton JL, Khanna S, Giles PJ, Brennan P, Brewis IA, Staffurth J, Mason MD, Clayton A."
Journal name MCP
Publication year 2010
Sample Bladder cancer cells
Sample name HT1376
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.10-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF/TOF]
Western blotting
FACS
5
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 1333
MISEV standards
Biophysical techniques
✔
CD81|EPCAM|CD9
Enriched markers
✘ Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35918900    
Organism Homo sapiens
Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL)
Authors "Bauzá-Martinez J, Armony G, Pronker MF, Wu W. "
Journal name J Extracell Vesicles
Publication year 2022
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectometry
Western blotting
10
Experiment ID 1335
MISEV standards
Biophysical techniques
✔
EPCAM|CD9
Enriched markers
✘ Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35918900    
Organism Homo sapiens
Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL)
Authors "Bauzá-Martinez J, Armony G, Pronker MF, Wu W. "
Journal name J Extracell Vesicles
Publication year 2022
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectometry
11
Experiment ID 494
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD151|CD63|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Osteoarthritic cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
12
Experiment ID 496
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Healthy cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
13
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
14
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
15
Experiment ID 20
MISEV standards
✔
EM
Biophysical techniques
✔
HSP90|CD63|CD81|LAMP1
Enriched markers
✔
GOLGA2|cytochrome c
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17956143    
Organism Homo sapiens
Experiment description Proteomic analysis of microvesicles derived from human colorectal cancer cells.
Authors "Choi DS, Lee JM, Park GW, Lim HW, Bang JY, Kim YK, Kwon KH, Kwon HJ, Kim KP, Gho YS"
Journal name JPR
Publication year 2007
Sample Colorectal cancer cells
Sample name HT29
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Diafiltration
Flotation density 1.16 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
16
Experiment ID 207
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
17
Experiment ID 208
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
18
Experiment ID 209
MISEV standards
✘ Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
19
Experiment ID 283
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Ultracentrifugation - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
20
Experiment ID 1203
MISEV standards
✔
EM
Biophysical techniques
✔
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
21
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
22
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
23
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
24
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
25
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
26
Experiment ID 226
MISEV standards
✔
EM
Biophysical techniques
✔
GAPDH|CD9|FLOT1
Enriched markers
✔
LMNA|H2AFX|ATP5A1|TOMM20
Negative markers
✘ Particle analysis
Identified molecule mRNA
Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
PubMed ID 26027894    
Organism Homo sapiens
Experiment description "Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting"
Authors "Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar"
Journal name Journal of Extracellular Vesicles
Publication year 2015
Sample Endothelial cells
Sample name HMEC-1
Isolation/purification methods Differential ultracentrifugation
Sucrose density gradient
Flotation density 1.10 g/mL
Molecules identified in the study miRNA
Protein
snoRNA
lncRNA
yRNA
snRNA
mRNA
ncRNA
mtRNA
vtRNA
scaRNA
lincRNA
Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
Western blotting
27
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
28
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
29
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
30
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
31
Experiment ID 234
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-C3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
32
Experiment ID 235
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
33
Experiment ID 236
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
34
Experiment ID 237
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
35
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
36
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
37
Experiment ID 254
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name MNT-1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
38
Experiment ID 255
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name G1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
39
Experiment ID 256
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 501mel
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
40
Experiment ID 257
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name Daju
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
41
Experiment ID 258
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name SKMEL28
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
42
Experiment ID 259
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name A375M
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
43
Experiment ID 260
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 1205Lu
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
44
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
45
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
46
Experiment ID 219
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|CD9
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25857718    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from nasopharyngeal carcinoma cell identifies intercellular transfer of angiogenic proteins
Authors "Chan YK, Zhang H, Liu P, Tsao GS, Li Lung M, Mak NK, Ngok-Shun Wong R, Ying-Kit Yue P"
Journal name Int J Cancer
Publication year 2015
Sample Nasopharyngeal carcinoma cells
Sample name C666-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.17-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
47
Experiment ID 220
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|CD9
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25857718    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from nasopharyngeal carcinoma cell identifies intercellular transfer of angiogenic proteins
Authors "Chan YK, Zhang H, Liu P, Tsao GS, Li Lung M, Mak NK, Ngok-Shun Wong R, Ying-Kit Yue P"
Journal name Int J Cancer
Publication year 2015
Sample Nasopharyngeal carcinoma cells
Sample name NP69
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.17-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
48
Experiment ID 221
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|CD9
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25857718    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from nasopharyngeal carcinoma cell identifies intercellular transfer of angiogenic proteins
Authors "Chan YK, Zhang H, Liu P, Tsao GS, Li Lung M, Mak NK, Ngok-Shun Wong R, Ying-Kit Yue P"
Journal name Int J Cancer
Publication year 2015
Sample Nasopharyngeal carcinoma cells
Sample name NP460
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.17-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
49
Experiment ID 224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
50
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
51
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
52
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
53
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
54
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
55
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
56
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
57
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
58
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
59
Experiment ID 231
MISEV standards
✘ Biophysical techniques
✔
Alix|CD63|CD9
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Western blotting
Mass spectrometry
60
Experiment ID 232
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
61
Experiment ID 233
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
62
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
63
Experiment ID 275
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel sensitive
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.12-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry/Flow cytometry/Western blotting
64
Experiment ID 274
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel resistant
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.18 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Flow cytometry
Western blotting
65
Experiment ID 191
MISEV standards
✘ Biophysical techniques
✔
Alix|CD81|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
66
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
67
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
68
Experiment ID 63
MISEV standards
✘ Biophysical techniques
✔
AQP2
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for PCBP1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 EIF3A 8661
Proximity Label-MS Homo sapiens
2 HDAC4  
Affinity Capture-MS Homo sapiens
3 FRK 2444
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 UBL4A 8266
Affinity Capture-MS Homo sapiens
5 EIF3C 8663
Proximity Label-MS Homo sapiens
6 PRPF8 10594
Two-hybrid Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Luminescence Homo sapiens
7 PKM 5315
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
8 SRPK2 6733
Affinity Capture-MS Homo sapiens
9 AES 166
Two-hybrid Homo sapiens
10 EBNA-LP  
Affinity Capture-MS
11 Aif1l  
Affinity Capture-MS Mus musculus
12 MAP4 4134
Proximity Label-MS Homo sapiens
13 KIF20A 10112
Affinity Capture-MS Homo sapiens
14 SLC25A1 6576
Affinity Capture-MS Homo sapiens
15 RBM12 10137
Co-fractionation Homo sapiens
16 ISG15 9636
Affinity Capture-MS Homo sapiens
17 SEPT2 4735
Proximity Label-MS Homo sapiens
18 PRKDC 5591
Proximity Label-MS Homo sapiens
19 PCBP3 54039
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
20 POLH  
Affinity Capture-RNA Homo sapiens
21 IGF2BP3 10643
Two-hybrid Homo sapiens
22 WDR76  
Affinity Capture-MS Homo sapiens
23 TRMT1L 81627
Affinity Capture-MS Homo sapiens
24 DARS 1615
Proximity Label-MS Homo sapiens
25 KIF23 9493
Affinity Capture-MS Homo sapiens
26 CPSF7 79869
Affinity Capture-MS Homo sapiens
27 NPRL2  
Affinity Capture-MS Homo sapiens
28 SMC2 10592
Proximity Label-MS Homo sapiens
29 RPS9 6203
Affinity Capture-MS Homo sapiens
30 EIF3E 3646
Affinity Capture-MS Homo sapiens
31 DYNLL1 8655
Co-fractionation Homo sapiens
32 SOD1 6647
Co-fractionation Homo sapiens
33 EEF1A1 1915
Affinity Capture-MS Homo sapiens
34 RBM14 10432
Two-hybrid Homo sapiens
35 KIF14 9928
Affinity Capture-MS Homo sapiens
36 UNK  
Affinity Capture-RNA Homo sapiens
37 MPI 4351
Co-fractionation Homo sapiens
38 TRIAP1  
Co-fractionation Homo sapiens
39 ANXA7 310
Co-fractionation Homo sapiens
40 MTCH2 23788
Affinity Capture-MS Homo sapiens
41 RIN3  
Affinity Capture-MS Homo sapiens
42 CRY1  
Affinity Capture-MS Homo sapiens
43 RFC5 5985
Affinity Capture-MS Homo sapiens
44 PELO 53918
Affinity Capture-MS Homo sapiens
45 SRSF3 6428
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
46 TUFM 7284
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
47 RPL18A 6142
Affinity Capture-MS Homo sapiens
48 CIRH1A 84916
Affinity Capture-MS Homo sapiens
49 CDH1 999
Proximity Label-MS Homo sapiens
50 YAP1 10413
Affinity Capture-MS Homo sapiens
51 TRIM21 6737
Affinity Capture-MS Homo sapiens
52 SLX4  
Affinity Capture-MS Homo sapiens
53 RPL31 6160
Affinity Capture-MS Homo sapiens
54 XRCC5 7520
Proximity Label-MS Homo sapiens
55 SYNCRIP 10492
Affinity Capture-MS Homo sapiens
56 NOS2  
Affinity Capture-MS Homo sapiens
57 BICD2 23299
Proximity Label-MS Homo sapiens
58 HIST1H1C 3006
Proximity Label-MS Homo sapiens
59 CUL2 8453
Affinity Capture-MS Homo sapiens
60 SRPK3  
Affinity Capture-MS Homo sapiens
61 DDX39B 7919
Affinity Capture-MS Homo sapiens
62 SRPK1 6732
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
63 CCNT1  
Affinity Capture-MS Homo sapiens
64 SLC25A5 292
Affinity Capture-MS Homo sapiens
65 PIK3CB 5291
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
66 IGBP1 3476
Co-fractionation Homo sapiens
67 ANLN 54443
Affinity Capture-MS Homo sapiens
68 EIF3G 8666
Proximity Label-MS Homo sapiens
69 TMPO 7112
Affinity Capture-MS Homo sapiens
70 RBM39 9584
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
71 APOE 348
Affinity Capture-MS Homo sapiens
72 ZNF622 90441
Affinity Capture-MS Homo sapiens
73 CUL3 8452
Affinity Capture-MS Homo sapiens
74 DES 1674
Proximity Label-MS Homo sapiens
75 EBNA1BP2 10969
Affinity Capture-MS Homo sapiens
76 FAHD1 81889
Co-fractionation Homo sapiens
77 EPRS 2058
Proximity Label-MS Homo sapiens
78 EIF2S2 8894
Affinity Capture-MS Homo sapiens
79 RRP15  
Affinity Capture-MS Homo sapiens
80 FN1 2335
Affinity Capture-MS Homo sapiens
81 CAMSAP2  
Affinity Capture-MS Homo sapiens
82 PCBP1 5093
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
83 RPA3 6119
Proximity Label-MS Homo sapiens
84 EIF2D 1939
Affinity Capture-MS Homo sapiens
85 TIGAR 57103
Co-fractionation Homo sapiens
86 MYO9B 4650
Affinity Capture-MS Homo sapiens
87 HSPA1A 3303
Proximity Label-MS Homo sapiens
88 CARHSP1 23589
Co-fractionation Homo sapiens
89 GNL3 26354
Affinity Capture-MS Homo sapiens
90 RPS16 6217
Affinity Capture-MS Homo sapiens
91 U2SURP 23350
Affinity Capture-MS Homo sapiens
92 FASN 2194
Proximity Label-MS Homo sapiens
93 TIA1 7072
Co-fractionation Homo sapiens
94 PSAT1 29968
Co-fractionation Homo sapiens
95 RUVBL2 10856
Affinity Capture-MS Homo sapiens
96 TCERG1 10915
Affinity Capture-MS Homo sapiens
97 CDC37 11140
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
98 RRP1 8568
Affinity Capture-MS Homo sapiens
99 TUBGCP3 10426
Affinity Capture-MS Homo sapiens
100 WRAP53  
Affinity Capture-MS Homo sapiens
101 ZC2HC1A 51101
Affinity Capture-MS Homo sapiens
102 BMPR1A 657
Affinity Capture-MS Homo sapiens
103 TKT 7086
Co-fractionation Homo sapiens
104 HSP90AA1 3320
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
105 PUF60 22827
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
106 BOLA2 552900
Affinity Capture-MS Homo sapiens
107 H2AFY 9555
Proximity Label-MS Homo sapiens
108 NOVA1  
Two-hybrid Homo sapiens
109 ERCC3  
Affinity Capture-MS Homo sapiens
110 WWP2 11060
Affinity Capture-MS Homo sapiens
111 DARS-AS1  
Protein-RNA Homo sapiens
112 NCL 4691
Proximity Label-MS Homo sapiens
113 HNRNPL 3191
Affinity Capture-MS Homo sapiens
114 HNRNPLL 92906
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
115 ACO2 50
Affinity Capture-MS Homo sapiens
116 PRPF4 9128
Affinity Capture-MS Homo sapiens
117 HNF1B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
118 LUC7L 55692
Affinity Capture-MS Homo sapiens
119 REPIN1  
Affinity Capture-MS Homo sapiens
120 RANGAP1 5905
Proximity Label-MS Homo sapiens
121 HNRNPH1 3187
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
122 ACOT7 11332
Co-fractionation Homo sapiens
123 SMC3 9126
Affinity Capture-MS Homo sapiens
124 NCBP1 4686
Affinity Capture-MS Homo sapiens
125 SPRTN  
Affinity Capture-MS Homo sapiens
126 ANP32A 8125
Two-hybrid Homo sapiens
127 CTBP2 1488
Affinity Capture-MS Homo sapiens
128 TARDBP 23435
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
129 BTF3 689
Affinity Capture-MS Homo sapiens
130 NACA 4666
Proximity Label-MS Homo sapiens
131 ADRB2  
Affinity Capture-MS Homo sapiens
132 QKI 9444
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
133 LGALS1 3956
Co-fractionation Homo sapiens
134 CORO7 79585
Proximity Label-MS Homo sapiens
135 RPL14 9045
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
136 CAND1 55832
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
137 CPT1A 1374
Co-fractionation Homo sapiens
138 GRHPR 9380
Co-fractionation Homo sapiens
139 ARIH1 25820
Proximity Label-MS Homo sapiens
Two-hybrid Homo sapiens
140 B3GNT2 10678
Affinity Capture-MS Homo sapiens
141 TUBB 203068
Affinity Capture-MS Homo sapiens
142 RBM3 5935
Two-hybrid Homo sapiens
143 DPYSL2 1808
Proximity Label-MS Homo sapiens
144 DDX24 57062
Affinity Capture-MS Homo sapiens
145 TLN1 7094
Proximity Label-MS Homo sapiens
146 RFC3 5983
Affinity Capture-MS Homo sapiens
147 TAF15 8148
Affinity Capture-MS Homo sapiens
148 KHDRBS1 10657
Affinity Capture-MS Homo sapiens
149 OBSL1 23363
Affinity Capture-MS Homo sapiens
150 PRDX2 7001
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
151 BAX 581
Co-fractionation Homo sapiens
152 FBXO11  
Affinity Capture-MS Homo sapiens
153 STIP1 10963
Co-fractionation Homo sapiens
154 VCAM1 7412
Affinity Capture-MS Homo sapiens
155 DDX6 1656
Affinity Capture-MS Homo sapiens
156 TIAL1 7073
Co-fractionation Homo sapiens
157 CUL1 8454
Affinity Capture-MS Homo sapiens
158 RBM42  
Two-hybrid Homo sapiens
159 UGP2 7360
Two-hybrid Homo sapiens
160 DHX36 170506
Affinity Capture-MS Homo sapiens
161 PFKM 5213
Co-fractionation Homo sapiens
162 CELF3  
Two-hybrid Homo sapiens
163 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
164 RPL4 6124
Affinity Capture-MS Homo sapiens
165 WHSC1 7468
Proximity Label-MS Homo sapiens
166 RAI14 26064
Proximity Label-MS Homo sapiens
167 MYO6 4646
Proximity Label-MS Homo sapiens
168 UBAP2L 9898
Proximity Label-MS Homo sapiens
169 RECQL 5965
Affinity Capture-MS Homo sapiens
170 ACIN1 22985
Affinity Capture-MS Homo sapiens
171 RAD18  
Affinity Capture-MS Homo sapiens
172 LUC7L2 51631
Affinity Capture-MS Homo sapiens
173 PKN1 5585
Proximity Label-MS Homo sapiens
174 AKR1A1 10327
Co-fractionation Homo sapiens
175 RPLP0 6175
Affinity Capture-MS Homo sapiens
176 CYLD  
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
177 RPL30 6156
Affinity Capture-MS Homo sapiens
178 C16orf96  
Proximity Label-MS Homo sapiens
179 KDF1  
Affinity Capture-MS Homo sapiens
180 HNRNPD 3184
Co-fractionation Homo sapiens
Two-hybrid Homo sapiens
181 KIF1B 23095
Affinity Capture-MS Homo sapiens
182 PSMA3 5684
Affinity Capture-MS Homo sapiens
183 HNRNPF 3185
Proximity Label-MS Homo sapiens
184 SMARCAD1  
Affinity Capture-MS Homo sapiens
185 RPS2 6187
Affinity Capture-MS Homo sapiens
186 RC3H2  
Affinity Capture-MS Homo sapiens
187 UBE2L6 9246
Affinity Capture-MS Homo sapiens
188 WDR33 55339
Affinity Capture-MS Homo sapiens
189 TJP1 7082
Proximity Label-MS Homo sapiens
190 TUBB4B 10383
Affinity Capture-MS Homo sapiens
191 FUS 2521
Affinity Capture-MS Homo sapiens
192 HSP90AA5P 730211
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
193 FTH1 2495
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
194 TNRC6B  
Affinity Capture-MS Homo sapiens
195 UBL5 59286
Affinity Capture-MS Homo sapiens
196 WEE1 7465
Affinity Capture-MS Homo sapiens
197 PPIL3 53938
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
198 CDK2 1017
Affinity Capture-MS Homo sapiens
199 MAP2K3 5606
Affinity Capture-MS Homo sapiens
200 MYC  
Affinity Capture-MS Homo sapiens
201 ERG  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
202 ARHGAP4 393
Co-fractionation Homo sapiens
203 CSNK2A2 1459
Affinity Capture-MS Homo sapiens
204 MET 4233
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
205 DSTN 11034
Co-fractionation Homo sapiens
206 SNW1 22938
Affinity Capture-MS Homo sapiens
207 DDRGK1 65992
Affinity Capture-MS Homo sapiens
208 NOP16 51491
Affinity Capture-MS Homo sapiens
209 MPRIP 23164
Proximity Label-MS Homo sapiens
210 LMNA 4000
Co-fractionation Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
211 RPL26 6154
Affinity Capture-MS Homo sapiens
212 RPL35A 6165
Affinity Capture-MS Homo sapiens
213 HUWE1 10075
Affinity Capture-MS Homo sapiens
214 RPL19 6143
Affinity Capture-MS Homo sapiens
215 RPL13 6137
Proximity Label-MS Homo sapiens
216 EIF3F 8665
Proximity Label-MS Homo sapiens
217 GIGYF2 26058
Proximity Label-MS Homo sapiens
218 TERF2  
Affinity Capture-MS Homo sapiens
219 PARP1 142
Proximity Label-MS Homo sapiens
220 ILF3 3609
Affinity Capture-MS Homo sapiens
221 ATXN3 4287
Affinity Capture-MS Homo sapiens
222 TP53 7157
Affinity Capture-MS Homo sapiens
223 CRIP1 1396
Co-fractionation Homo sapiens
224 PHF3  
Affinity Capture-MS Homo sapiens
225 RPS4X 6191
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
226 RPL23 9349
Affinity Capture-MS Homo sapiens
227 OTUB1 55611
Affinity Capture-MS Homo sapiens
228 ZNF281  
Affinity Capture-MS Homo sapiens
229 CDK1 983
Co-fractionation Homo sapiens
230 ESR1  
Affinity Capture-MS Homo sapiens
231 BCL2L1 598
Affinity Capture-MS Homo sapiens
232 EEF1D 1936
Co-fractionation Homo sapiens
233 RPL7A 6130
Affinity Capture-MS Homo sapiens
234 TCF3  
Affinity Capture-MS Homo sapiens
235 EIF2AK2 5610
Affinity Capture-MS Homo sapiens
236 KRAS 3845
Negative Genetic Homo sapiens
237 MAST3  
Affinity Capture-MS Homo sapiens
238 PRMT1 3276
Affinity Capture-MS Homo sapiens
239 ZNF830  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Luminescence Homo sapiens
240 TCP1 6950
Proximity Label-MS Homo sapiens
241 COTL1 23406
Co-fractionation Homo sapiens
242 RALY 22913
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
243 HNRNPC 3183
Affinity Capture-MS Homo sapiens
244 HEBP1 50865
Co-fractionation Homo sapiens
245 TCEB1 6921
Affinity Capture-MS Homo sapiens
246 IDH1 3417
Co-fractionation Homo sapiens
247 PFKP 5214
Co-fractionation Homo sapiens
248 YWHAE 7531
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
249 CAPZA1 829
Proximity Label-MS Homo sapiens
250 MRE11A 4361
Proximity Label-MS Homo sapiens
251 FUBP3 8939
Co-fractionation Homo sapiens
252 HNRNPR 10236
Affinity Capture-MS Homo sapiens
253 MAP4K3 8491
Affinity Capture-MS Homo sapiens
254 RPS6KB2  
Affinity Capture-MS Homo sapiens
255 PCGF2 7703
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
256 ADK 132
Co-fractionation Homo sapiens
257 DIMT1 27292
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
258 CRYBB1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
259 RUVBL1 8607
Affinity Capture-MS Homo sapiens
260 TRIM28 10155
Affinity Capture-MS Homo sapiens
261 TCEB2 6923
Affinity Capture-MS Homo sapiens
262 MCM2 4171
Affinity Capture-MS Homo sapiens
263 DAZAP1 26528
Co-fractionation Homo sapiens
264 TRIM56 81844
Affinity Capture-RNA Homo sapiens
265 EWSR1 2130
Two-hybrid Homo sapiens
266 SF3A2 8175
Affinity Capture-MS Homo sapiens
267 ITGA4 3676
Affinity Capture-MS Homo sapiens
268 CYR61 3491
Affinity Capture-MS Homo sapiens
269 RPS3A 6189
Affinity Capture-MS Homo sapiens
270 ARGLU1  
Affinity Capture-MS Homo sapiens
271 MRPL4 51073
Affinity Capture-MS Homo sapiens
272 CAV3 859
Two-hybrid Homo sapiens
273 RPL27 6155
Affinity Capture-MS Homo sapiens
274 ACAT2 39
Co-fractionation Homo sapiens
275 C2orf27B  
Affinity Capture-MS Homo sapiens
276 RPL9 6133
Affinity Capture-MS Homo sapiens
277 TAF10 6881
Affinity Capture-MS Homo sapiens
278 PARK2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
279 COPE 11316
Affinity Capture-MS Homo sapiens
280 MEX3C 51320
Affinity Capture-MS Homo sapiens
281 GOLGA2 2801
Affinity Capture-MS Homo sapiens
282 RPL5 6125
Affinity Capture-MS Homo sapiens
283 HIST1H1D 3007
Affinity Capture-MS Homo sapiens
284 RASSF9  
Affinity Capture-MS Homo sapiens
285 CHMP4B 128866
Affinity Capture-MS Homo sapiens
286 FUBP1 8880
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
287 RAN 5901
Affinity Capture-MS Homo sapiens
288 NTRK1 4914
Affinity Capture-MS Homo sapiens
289 PABPC1 26986
Co-fractionation Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
290 U2AF2 11338
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
291 RPL36 25873
Affinity Capture-MS Homo sapiens
292 SMAD2 4087
Affinity Capture-MS Homo sapiens
293 RPA4  
Proximity Label-MS Homo sapiens
294 PIK3R1 5295
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
295 DHX9 1660
Affinity Capture-MS Homo sapiens
296 HNRNPA3 220988
Affinity Capture-MS Homo sapiens
297 HMGB2 3148
Two-hybrid Homo sapiens
298 RBM10  
Two-hybrid Homo sapiens
299 PCBP2 5094
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
300 RBBP6 5930
Affinity Capture-MS Homo sapiens
301 OGT 8473
Reconstituted Complex Homo sapiens
302 ZBTB2 57621
Affinity Capture-MS Homo sapiens
303 GLOD4 51031
Co-fractionation Homo sapiens
304 METTL14  
Affinity Capture-MS Homo sapiens
305 DDX3Y 8653
Affinity Capture-MS Homo sapiens
306 ECT2 1894
Affinity Capture-MS Homo sapiens
307 EEF2 1938
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
308 HYPK 25764
Two-hybrid Homo sapiens
309 HSP90AB1 3326
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
310 SF1 7536
Affinity Capture-MS Homo sapiens
311 FBXO6 26270
Affinity Capture-MS Homo sapiens
312 BOLA1 51027
Co-fractionation Homo sapiens
313 CELF2 10659
Two-hybrid Homo sapiens
314 OCIAD1 54940
Co-fractionation Homo sapiens
315 RFC1 5981
Affinity Capture-MS Homo sapiens
316 AP2M1 1173
Affinity Capture-MS Homo sapiens
317 MYO1D 4642
Proximity Label-MS Homo sapiens
318 FXR2 9513
Affinity Capture-MS Homo sapiens
319 RPS14 6208
Affinity Capture-MS Homo sapiens
320 RPL12 6136
Affinity Capture-MS Homo sapiens
321 PIK3CA 5290
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
322 MATR3 9782
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
323 HDLBP 3069
Proximity Label-MS Homo sapiens
324 RPL18 6141
Affinity Capture-MS Homo sapiens
325 HSPA9 3313
Co-fractionation Homo sapiens
326 RBM17 84991
Affinity Capture-MS Homo sapiens
327 HIF1A 3091
Affinity Capture-MS Homo sapiens
328 TUBB2A 7280
Co-fractionation Homo sapiens
329 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
330 CCT8 10694
Proximity Label-MS Homo sapiens
331 RPS25 6230
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
332 IMPDH2 3615
Affinity Capture-MS Homo sapiens
333 RPL6 6128
Affinity Capture-MS Homo sapiens
334 TALDO1 6888
Co-fractionation Homo sapiens
335 MCM5 4174
Affinity Capture-MS Homo sapiens
336 PPP1CC 5501
Affinity Capture-MS Homo sapiens
337 SNRPA 6626
Two-hybrid Homo sapiens
338 HNRNPM 4670
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
339 THRAP3 9967
Affinity Capture-MS Homo sapiens
340 PTBP3 9991
Affinity Capture-MS Homo sapiens
341 SETMAR  
Affinity Capture-MS Homo sapiens
342 MKI67  
Affinity Capture-MS Homo sapiens
343 TUBB6 84617
Co-fractionation Homo sapiens
344 UFL1 23376
Affinity Capture-MS Homo sapiens
345 MIF 4282
Co-fractionation Homo sapiens
346 TAGLN2 8407
Proximity Label-MS Homo sapiens
347 RPL38 6169
Proximity Label-MS Homo sapiens
348 API5 8539
Affinity Capture-MS Homo sapiens
349 HNRNPH3 3189
Affinity Capture-MS Homo sapiens
350 FLNA 2316
Proximity Label-MS Homo sapiens
351 RPL8 6132
Affinity Capture-MS Homo sapiens
352 METTL3  
Affinity Capture-MS Homo sapiens
353 RPL28 6158
Affinity Capture-MS Homo sapiens
354 SERBP1 26135
Affinity Capture-MS Homo sapiens
355 RC3H1 149041
Affinity Capture-MS Homo sapiens
356 MRPS22 56945
Affinity Capture-MS Homo sapiens
357 HARS 3035
Co-fractionation Homo sapiens
358 IGF2BP2 10644
Affinity Capture-MS Homo sapiens
359 EP300 2033
Affinity Capture-MS Homo sapiens
360 HSPA2 3306
Proximity Label-MS Homo sapiens
361 UBE2H 7328
Affinity Capture-MS Homo sapiens
362 TNFAIP3 7128
Two-hybrid Homo sapiens
363 RIT1 6016
Negative Genetic Homo sapiens
364 XIAP  
Affinity Capture-MS Homo sapiens
365 CCT3 7203
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
366 POT1  
Affinity Capture-MS Homo sapiens
367 PTBP1 5725
Co-fractionation Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
368 RABEP2 79874
Affinity Capture-MS Homo sapiens
369 PPIE 10450
Affinity Capture-MS Homo sapiens
370 RACGAP1 29127
Affinity Capture-MS Homo sapiens
371 UBE2M 9040
Co-fractionation Homo sapiens
372 ATP6V1C1 528
Co-fractionation Homo sapiens
373 RPL13A 23521
Affinity Capture-MS Homo sapiens
374 TRUB2  
Affinity Capture-MS Homo sapiens
375 SIVA1  
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
376 PAICS 10606
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
377 CD2AP 23607
Proximity Label-MS Homo sapiens
378 HSPA1L 3305
Proximity Label-MS Homo sapiens
379 ESF1 51575
Affinity Capture-MS Homo sapiens
380 RPL10 6134
Affinity Capture-MS Homo sapiens
381 RPL15 6138
Affinity Capture-MS Homo sapiens
382 CCT4 10575
Proximity Label-MS Homo sapiens
383 PRPF3  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
384 DVL3 1857
Affinity Capture-MS Homo sapiens
385 SRP72 6731
Affinity Capture-MS Homo sapiens
386 CFL1 1072
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
387 APP 351
Reconstituted Complex Homo sapiens
388 HSPA5 3309
Proximity Label-MS Homo sapiens
389 ILF2 3608
Affinity Capture-MS Homo sapiens
390 USP36  
Affinity Capture-MS Homo sapiens
391 CTSD 1509
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
392 TOP2A 7153
Proximity Label-MS Homo sapiens
393 RPS20 6224
Proximity Label-MS Homo sapiens
394 TSC22D4 81628
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
395 PRC1 9055
Affinity Capture-MS Homo sapiens
396 TGFB1 7040
Affinity Capture-MS Homo sapiens
397 PITPNB 23760
Co-fractionation Homo sapiens
398 ATXN2L 11273
Affinity Capture-MS Homo sapiens
399 KIF5B 3799
Proximity Label-MS Homo sapiens
400 Cep55 74107
Affinity Capture-MS Mus musculus
401 COPS5 10987
Affinity Capture-MS Homo sapiens
402 FBXW7  
Affinity Capture-MS Homo sapiens
403 RPL24 6152
Affinity Capture-MS Homo sapiens
404 PSMC6 5706
Cross-Linking-MS (XL-MS) Homo sapiens
405 PRKRA 8575
Affinity Capture-MS Homo sapiens
406 EED  
Affinity Capture-MS Homo sapiens
407 HNRNPK 3190
Cross-Linking-MS (XL-MS) Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
408 CDC73  
Affinity Capture-MS Homo sapiens
409 MYCN  
Affinity Capture-MS Homo sapiens
410 ADSS 159
Affinity Capture-MS Homo sapiens
411 CTCF  
Affinity Capture-MS Homo sapiens
412 KPNA3 3839
Affinity Capture-MS Homo sapiens
413 RPS26 6231
Affinity Capture-MS Homo sapiens
414 LSM12 124801
Co-fractionation Homo sapiens
415 ADSL 158
Affinity Capture-MS Homo sapiens
416 C1orf106  
Affinity Capture-MS Homo sapiens
417 RPS23 6228
Affinity Capture-MS Homo sapiens
418 MED20 9477
Affinity Capture-MS Homo sapiens
419 MRPS34 65993
Affinity Capture-MS Homo sapiens
420 ANXA11 311
Co-fractionation Homo sapiens
421 STAU1 6780
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
422 CPS1 1373
Co-fractionation Homo sapiens
423 SRSF6 6431
Affinity Capture-MS Homo sapiens
424 ATF2  
Affinity Capture-MS Homo sapiens
425 VCP 7415
Affinity Capture-MS Homo sapiens
426 DDX5 1655
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
427 AHNAK 79026
Proximity Label-MS Homo sapiens
428 DCTN1 1639
Affinity Capture-MS Homo sapiens
429 RPL27A 6157
Affinity Capture-MS Homo sapiens
430 CRY2  
Affinity Capture-MS Homo sapiens
431 SMC1A 8243
Affinity Capture-MS Homo sapiens
432 EIF4G2 1982
Proximity Label-MS Homo sapiens
433 DYNLL2 140735
Co-fractionation Homo sapiens
434 FAM49B 51571
Co-fractionation Homo sapiens
435 UPF1 5976
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
436 RPS15A 6210
Affinity Capture-MS Homo sapiens
437 ATP5B 506
Proximity Label-MS Homo sapiens
438 PPAN 56342
Affinity Capture-MS Homo sapiens
439 SFPQ 6421
Affinity Capture-MS Homo sapiens
440 GFER  
Co-fractionation Homo sapiens
441 RPLP2 6181
Affinity Capture-MS Homo sapiens
442 FANCD2  
Affinity Capture-MS Homo sapiens
443 KLF1  
Two-hybrid Homo sapiens
444 CDK9 1025
Affinity Capture-MS Homo sapiens
445 EIF4G1 1981
Proximity Label-MS Homo sapiens
446 CCT6A 908
Proximity Label-MS Homo sapiens
447 NAT10 55226
Affinity Capture-MS Homo sapiens
448 CTNNB1 1499
Affinity Capture-MS Homo sapiens
449 RPS6 6194
Affinity Capture-MS Homo sapiens
450 TXN 7295
Affinity Capture-MS Homo sapiens
451 CTTN 2017
Proximity Label-MS Homo sapiens
452 RPL3 6122
Affinity Capture-MS Homo sapiens
453 RPL7 6129
Affinity Capture-MS Homo sapiens
454 ECHS1 1892
Co-fractionation Homo sapiens
455 SART1 9092
Affinity Capture-MS Homo sapiens
456 EIF4A2 1974
Proximity Label-MS Homo sapiens
457 AURKB 9212
Affinity Capture-MS Homo sapiens
458 Csnk1e  
Affinity Capture-MS Mus musculus
459 HNRNPA1 3178
Affinity Capture-MS Homo sapiens
460 RASSF10  
Affinity Capture-MS Homo sapiens
461 UPF3B 65109
Affinity Capture-MS Homo sapiens
462 SF3B3 23450
Proximity Label-MS Homo sapiens
463 RPL11 6135
Affinity Capture-MS Homo sapiens
464 FSCN1 6624
Co-fractionation Homo sapiens
465 BMP4 652
Affinity Capture-MS Homo sapiens
466 DDX52  
Affinity Capture-MS Homo sapiens
467 GNB2L1 10399
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
468 RBM11  
Two-hybrid Homo sapiens
469 FAM120A 23196
Affinity Capture-MS Homo sapiens
470 TRIP6 7205
Co-fractionation Homo sapiens
471 PDLIM7 9260
Two-hybrid Homo sapiens
472 ACP1 52
Co-fractionation Homo sapiens
473 SRRM1 10250
Affinity Capture-MS Homo sapiens
474 MRPS2 51116
Affinity Capture-MS Homo sapiens
475 NUDT11 55190
Affinity Capture-MS Homo sapiens
476 ERH 2079
Affinity Capture-MS Homo sapiens
477 PPIG 9360
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
478 NUFIP2 57532
Affinity Capture-MS Homo sapiens
479 CUL5 8065
Affinity Capture-MS Homo sapiens
480 PDCD6 10016
Co-fractionation Homo sapiens
481 NDUFS7 374291
Affinity Capture-MS Homo sapiens
482 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
483 ARF4 378
Affinity Capture-MS Homo sapiens
484 PCBP4 57060
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
485 RBFOX2 23543
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
486 KIAA1429 25962
Affinity Capture-MS Homo sapiens
487 OTUD4  
Affinity Capture-MS Homo sapiens
488 TRIP4 9325
Affinity Capture-MS Homo sapiens
489 TRIM31  
Affinity Capture-MS Homo sapiens
490 ZCCHC10  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
491 RBPMS2  
Two-hybrid Homo sapiens
492 RPS8 6202
Affinity Capture-MS Homo sapiens
493 XRCC6 2547
Proximity Label-MS Homo sapiens
494 C9orf72  
Affinity Capture-MS Homo sapiens
495 WARS 7453
Co-fractionation Homo sapiens
496 MRPS18A  
Affinity Capture-MS Homo sapiens
497 CDC5L 988
Affinity Capture-MS Homo sapiens
498 CUL7 9820
Affinity Capture-MS Homo sapiens
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Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here