Gene description for EIF4EBP1
Gene name eukaryotic translation initiation factor 4E binding protein 1
Gene symbol EIF4EBP1
Other names/aliases -
Species Bos taurus
 Database cross references - EIF4EBP1
ExoCarta ExoCarta_509613
Entrez Gene 509613
UniProt Q0P5A7  
 EIF4EBP1 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for EIF4EBP1
Molecular Function
    translation repressor activity GO:0030371 ISS
    eukaryotic initiation factor 4E binding GO:0008190 IBA
Biological Process
    TOR signaling GO:0031929 ISS
    insulin receptor signaling pathway GO:0008286 IEA
    IRES-dependent translational initiation GO:0002192 IEA
    negative regulation of translational initiation GO:0045947 ISS
    positive regulation of mitotic cell cycle GO:0045931 IEA
    G1/S transition of mitotic cell cycle GO:0000082 IEA
Subcellular Localization
    cytoplasm GO:0005737 IBA
    nucleoplasm GO:0005654 IEA
 Experiment description of studies that identified EIF4EBP1 in exosomes
1
Experiment ID 213
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for EIF4EBP1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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