Gene description for PSME2
Gene name proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
Gene symbol PSME2
Other names/aliases -
Species Bos taurus
 Database cross references - PSME2
ExoCarta ExoCarta_509857
Vesiclepedia VP_509857
Entrez Gene 509857
UniProt Q5E9G3  
 PSME2 identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for PSME2
Molecular Function
    endopeptidase activator activity GO:0061133 IEA
Biological Process
    positive regulation of endopeptidase activity GO:0010950 IEA
    regulation of proteasomal protein catabolic process GO:0061136 IEA
    regulation of G1/S transition of mitotic cell cycle GO:2000045 IEA
Subcellular Localization
    nucleoplasm GO:0005654 IEA
    cytoplasm GO:0005737 IEA
    proteasome activator complex GO:0008537 IEA
 Experiment description of studies that identified PSME2 in sEVs
1
Experiment ID 213
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PSME2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which PSME2 is involved
PathwayEvidenceSource
Metabolism of proteins IEA Reactome
Post-translational protein modification IEA Reactome
Proteasome assembly IEA Reactome





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