Gene description for LIN7C
Gene name lin-7 homolog C (C. elegans)
Gene symbol LIN7C
Other names/aliases -
Species Bos taurus
 Database cross references - LIN7C
ExoCarta ExoCarta_510125
Entrez Gene 510125
UniProt Q0P5F3  
 LIN7C identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for LIN7C
Molecular Function
    cytoskeletal protein binding GO:0008092 IEA
    L27 domain binding GO:0097016 IBA
Biological Process
    neurotransmitter secretion GO:0007269 IBA
    protein localization to basolateral plasma membrane GO:1903361 IBA
    protein transport GO:0015031 IEA
    morphogenesis of an epithelial sheet GO:0002011 IEA
    maintenance of epithelial cell apical/basal polarity GO:0045199 IBA
    exocytosis GO:0006887 IBA
    asymmetric protein localization GO:0008105 IBA
Subcellular Localization
    neuron projection GO:0043005 IEA
    cell-cell junction GO:0005911 IBA
    bicellular tight junction GO:0005923 IEA
    extracellular exosome GO:0070062 IEA
    basolateral plasma membrane GO:0016323 IBA
    postsynaptic density GO:0014069 IEA
    MPP7-DLG1-LIN7 complex GO:0097025 IBA
    postsynaptic membrane GO:0045211 IEA
    synapse GO:0045202 IBA
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified LIN7C in exosomes
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for LIN7C
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which LIN7C is involved
Dopamine Neurotransmitter Release Cycle IEA Reactome

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