Gene description for FAM175B
Gene name family with sequence similarity 175, member B
Gene symbol FAM175B
Other names/aliases -
Species Bos taurus
 Database cross references - FAM175B
ExoCarta ExoCarta_510233
Vesiclepedia VP_510233
Entrez Gene 510233
UniProt A6QLR3  
 FAM175B identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for FAM175B
Molecular Function
    microtubule binding GO:0008017 IEA
    polyubiquitin modification-dependent protein binding GO:0031593 IEA
Biological Process
    attachment of spindle microtubules to kinetochore GO:0008608 IEA
    protein K63-linked deubiquitination GO:0070536 IEA
    mitotic spindle assembly GO:0090307 IEA
Subcellular Localization
    nucleus GO:0005634 IEA
 Experiment description of studies that identified FAM175B in sEVs
1
Experiment ID 213
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for FAM175B
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which FAM175B is involved
PathwayEvidenceSource
Deubiquitination IEA Reactome
Metabolism of proteins IEA Reactome
Metalloprotease DUBs IEA Reactome
Post-translational protein modification IEA Reactome





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