Gene description for PAH
Gene name phenylalanine hydroxylase
Gene symbol PAH
Other names/aliases -
Species Bos taurus
 Database cross references - PAH
ExoCarta ExoCarta_510583
Entrez Gene 510583
UniProt Q2KIH7  
 PAH identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for PAH
Molecular Function
    phenylalanine 4-monooxygenase activity GO:0004505 IEA
    iron ion binding GO:0005506 IEA
    amino acid binding GO:0016597 IEA
Biological Process
    oxidation-reduction process GO:0055114 IEA
    L-phenylalanine catabolic process GO:0006559 IEA
Subcellular Localization
    extracellular exosome GO:0070062 IEA
 Experiment description of studies that identified PAH in exosomes
1
Experiment ID 213
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PAH
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which PAH is involved
PathwayEvidenceSource
Phenylalanine and tyrosine catabolism IEA Reactome





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