Gene description for PAH
Gene name phenylalanine hydroxylase
Gene symbol PAH
Other names/aliases -
Species Bos taurus
 Database cross references - PAH
ExoCarta ExoCarta_510583
Entrez Gene 510583
UniProt Q2KIH7  
 PAH identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for PAH
Molecular Function
    phenylalanine 4-monooxygenase activity GO:0004505 IEA
    iron ion binding GO:0005506 IEA
    amino acid binding GO:0016597 IEA
Biological Process
    oxidation-reduction process GO:0055114 IEA
    L-phenylalanine catabolic process GO:0006559 IEA
Subcellular Localization
    extracellular exosome GO:0070062 IEA
 Experiment description of studies that identified PAH in exosomes
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PAH
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which PAH is involved
Phenylalanine and tyrosine catabolism IEA Reactome

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