Gene description for ALAD
Gene name aminolevulinate dehydratase
Gene symbol ALAD
Other names/aliases -
Species Bos taurus
 Database cross references - ALAD
ExoCarta ExoCarta_510679
Entrez Gene 510679
UniProt Q58DK5  
 ALAD identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for ALAD
Molecular Function
    identical protein binding GO:0042802 IEA
    lead ion binding GO:0032791 ISS
    zinc ion binding GO:0008270 ISS
    porphobilinogen synthase activity GO:0004655 ISS
Biological Process
    cellular response to interleukin-4 GO:0071353 IEA
    heme biosynthetic process GO:0006783 ISS
    protoporphyrinogen IX biosynthetic process GO:0006782 IEA
    protein homooligomerization GO:0051260 IEA
Subcellular Localization
    cytosol GO:0005829 IBA
    extracellular exosome GO:0070062 IEA
    nucleus GO:0005634 IEA
 Experiment description of studies that identified ALAD in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ALAD
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which ALAD is involved
PathwayEvidenceSource
Heme biosynthesis IEA Reactome





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