Gene description for PINK1
Gene name PTEN induced putative kinase 1
Gene symbol PINK1
Other names/aliases -
Species Bos taurus
 Database cross references - PINK1
ExoCarta ExoCarta_510683
Vesiclepedia VP_510683
Entrez Gene 510683
 PINK1 identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for PINK1
Molecular Function
    protein serine/threonine kinase activity GO:0004674 IEA
    ATP binding GO:0005524 IEA
Biological Process
    autophagy of mitochondrion GO:0000422 IEA
    protein phosphorylation GO:0006468 IEA
    regulation of apoptotic process GO:0042981 IEA
    positive regulation of mitochondrial fission GO:0090141 IEA
Subcellular Localization
    mitochondrion GO:0005739 IEA
 Experiment description of studies that identified PINK1 in sEVs
1
Experiment ID 213
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PINK1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which PINK1 is involved
No pathways found





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