Gene description for HARS
Gene name histidyl-tRNA synthetase
Gene symbol HARS
Other names/aliases HARSL
Species Bos taurus
 Database cross references - HARS
ExoCarta ExoCarta_510937
Entrez Gene 510937
UniProt Q2KI84  
 HARS identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for HARS
Molecular Function
    ATP binding GO:0005524 IEA
    histidine-tRNA ligase activity GO:0004821 IBA
Biological Process
    histidyl-tRNA aminoacylation GO:0006427 IBA
    mitochondrial translation GO:0032543 IBA
Subcellular Localization
    cytoplasm GO:0005737 IBA
    mitochondrion GO:0005739 IBA
 Experiment description of studies that identified HARS in exosomes
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for HARS
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which HARS is involved
No pathways found

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