Gene description for ADSL
Gene name adenylosuccinate lyase
Gene symbol ADSL
Other names/aliases -
Species Bos taurus
 Database cross references - ADSL
ExoCarta ExoCarta_510949
Entrez Gene 510949
UniProt A3KN12  
 ADSL identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for ADSL
Molecular Function
    N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity GO:0004018 IEA
    (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity GO:0070626 IEA
Biological Process
    'de novo' IMP biosynthetic process GO:0006189 IEA
    'de novo' AMP biosynthetic process GO:0044208 IEA
 Experiment description of studies that identified ADSL in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ADSL
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which ADSL is involved
No pathways found





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