Gene description for PMM2
Gene name phosphomannomutase 2
Gene symbol PMM2
Other names/aliases -
Species Bos taurus
 Database cross references - PMM2
ExoCarta ExoCarta_510978
Entrez Gene 510978
UniProt Q3SZJ9  
 PMM2 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for PMM2
Molecular Function
    phosphomannomutase activity GO:0004615 IEA
Biological Process
    GDP-mannose biosynthetic process GO:0009298 IEA
    mannose biosynthetic process GO:0019307 IEA
Subcellular Localization
    extracellular exosome GO:0070062 IEA
    neuronal cell body GO:0043025 IEA
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified PMM2 in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PMM2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which PMM2 is involved
PathwayEvidenceSource
Synthesis of GDP-mannose IEA Reactome





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