Gene description for PMM2
Gene name phosphomannomutase 2
Gene symbol PMM2
Other names/aliases -
Species Bos taurus
 Database cross references - PMM2
ExoCarta ExoCarta_510978
Entrez Gene 510978
UniProt Q3SZJ9  
 PMM2 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for PMM2
Molecular Function
    phosphomannomutase activity GO:0004615 IEA
Biological Process
    GDP-mannose biosynthetic process GO:0009298 IEA
    mannose biosynthetic process GO:0019307 IEA
Subcellular Localization
    extracellular exosome GO:0070062 IEA
    neuronal cell body GO:0043025 IEA
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified PMM2 in exosomes
1
Experiment ID 213
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PMM2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which PMM2 is involved
PathwayEvidenceSource
Synthesis of GDP-mannose IEA Reactome





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