Gene description for CDC42EP1
Gene name CDC42 effector protein (Rho GTPase binding) 1
Gene symbol CDC42EP1
Other names/aliases -
Species Bos taurus
 Database cross references - CDC42EP1
ExoCarta ExoCarta_511099
Entrez Gene 511099
UniProt Q17QW1  
 CDC42EP1 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for CDC42EP1
Molecular Function
    GTP-Rho binding GO:0017049 IBA
    GTPase activator activity GO:0005096 IBA
Biological Process
    positive regulation of actin filament polymerization GO:0030838 IBA
    regulation of cell shape GO:0008360 IBA
    positive regulation of GTPase activity GO:0043547 IBA
    positive regulation of pseudopodium assembly GO:0031274 IBA
    Rho protein signal transduction GO:0007266 IBA
Subcellular Localization
    plasma membrane GO:0005886 IBA
    Golgi apparatus GO:0005794 IEA
    cytoskeleton GO:0005856 IBA
    focal adhesion GO:0005925 IEA
    actin cytoskeleton GO:0015629 IEA
    cytoplasm GO:0005737 IBA
 Experiment description of studies that identified CDC42EP1 in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for CDC42EP1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which CDC42EP1 is involved
No pathways found





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