Gene description for RAB18
Gene name RAB18, member RAS oncogene family
Gene symbol RAB18
Other names/aliases -
Species Bos taurus
 Database cross references - RAB18
ExoCarta ExoCarta_511160
Entrez Gene 511160
UniProt Q0IIG8  
 RAB18 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for RAB18
Molecular Function
    GDP binding GO:0019003 ISS
    GTP binding GO:0005525 IEA
    GTPase activity GO:0003924 IBA
Biological Process
    eye development GO:0001654 ISS
    brain development GO:0007420 ISS
    Rab protein signal transduction GO:0032482 IBA
    intracellular protein transport GO:0006886 IBA
    endoplasmic reticulum tubular network organization GO:0071786 IEA
    lipid particle organization GO:0034389 IBA
    metabolic process GO:0008152 IBA
Subcellular Localization
    Golgi apparatus GO:0005794 IBA
    plasma membrane GO:0005886 IEA
    extracellular exosome GO:0070062 IEA
    endoplasmic reticulum tubular network GO:0071782 IEA
 Experiment description of studies that identified RAB18 in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for RAB18
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which RAB18 is involved
No pathways found





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