Gene description for CD81
Gene name CD81 molecule
Gene symbol CD81
Other names/aliases -
Species Bos taurus
 Database cross references - CD81
ExoCarta ExoCarta_511435
Entrez Gene 511435
UniProt Q3ZCD0  
 CD81 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for CD81
Molecular Function
    MHC class II protein complex binding GO:0023026 IEA
Biological Process
    positive regulation of B cell proliferation GO:0030890 IEA
    positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 IEA
    positive regulation of 1-phosphatidylinositol 4-kinase activity GO:0043128 IEA
    protein localization GO:0008104 IEA
    activation of MAPK activity GO:0000187 IEA
    phosphatidylinositol biosynthetic process GO:0006661 IEA
    regulation of cell motility GO:2000145 IEA
Subcellular Localization
    extracellular exosome GO:0070062 IEA
    focal adhesion GO:0005925 IEA
    immunological synapse GO:0001772 IEA
    integral component of plasma membrane GO:0005887 IEA
 Experiment description of studies that identified CD81 in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for CD81
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which CD81 is involved
PathwayEvidenceSource
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell IEA Reactome





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