Gene description for CLDN18
Gene name	claudin 18
Gene symbol	CLDN18
Other names/aliases	SFTA5 SFTPJ
Species	Homo sapiens
Database cross references - CLDN18
ExoCarta	ExoCarta_51208
Vesiclepedia	VP_51208
Entrez Gene	51208
HGNC	2039
MIM	609210
UniProt	P56856
CLDN18 identified in sEVs derived from the following tissue/cell type
Urine	21595033
Urine	21595033
Urine	21595033

Gene ontology annotations for CLDN18

Molecular Function     structural molecule activity GO:0005198 IEA     protein binding GO:0005515 IPI     identical protein binding GO:0042802 ISS Biological Process     cell adhesion GO:0007155 IBA     negative regulation of tumor necrosis factor-mediated signaling pathway GO:0010804 IEA     calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules GO:0016338 ISS     protein localization to nucleus GO:0034504 IEA     organ growth GO:0035265 ISS     epithelial fluid transport GO:0042045 ISS     response to ethanol GO:0045471 IEA     negative regulation of bone resorption GO:0045779 IEA     lung alveolus development GO:0048286 ISS     digestive tract development GO:0048565 IEA     epithelial cell proliferation GO:0050673 ISS     bicellular tight junction assembly GO:0070830 IBA     cellular response to estrogen stimulus GO:0071391 ISS     tight junction organization GO:0120193 ISS     negative regulation of protein localization to nucleus GO:1900181 ISS     negative regulation of osteoclast development GO:2001205 IEA Subcellular Localization     plasma membrane GO:0005886 IBA     plasma membrane GO:0005886 ISS     cell-cell junction GO:0005911 ISS     bicellular tight junction GO:0005923 IBA     bicellular tight junction GO:0005923 ISS     lateral plasma membrane GO:0016328 IEA