Gene description for HBA
Gene name hemoglobin, alpha 2
Gene symbol HBA
Other names/aliases HBA2
alpha globin
Species Bos taurus
 Database cross references - HBA
ExoCarta ExoCarta_512439
Vesiclepedia VP_512439
Entrez Gene 512439
UniProt P01966  
 HBA identified in sEVs derived from the following tissue/cell type
Serum 19327352    
 Gene ontology annotations for HBA
Molecular Function
    peroxidase activity GO:0004601 IEA
    oxygen carrier activity GO:0005344 IEA
    iron ion binding GO:0005506 IEA
    oxygen binding GO:0019825 IEA
    heme binding GO:0020037 IEA
    haptoglobin binding GO:0031720 IEA
    organic acid binding GO:0043177 IEA
Biological Process
    oxygen transport GO:0015671 IEA
    hydrogen peroxide catabolic process GO:0042744 IEA
Subcellular Localization
    hemoglobin complex GO:0005833 IEA
    haptoglobin-hemoglobin complex GO:0031838 IEA
    blood microparticle GO:0072562 IEA
 Experiment description of studies that identified HBA in sEVs
1
Experiment ID 187
MISEV standards
EM
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19327352    
Organism Bos taurus
Experiment description Anchorage-independent growth of breast carcinoma cells is mediated by serum exosomes.
Authors "Ochieng J, Pratap S, Khatua AK, Sakwe AM."
Journal name Exp Cell Res
Publication year 2009
Sample Serum
Sample name Normal - Fetal bovine serum
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for HBA
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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